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  • Genomic Medicine: Principles and Practice

    Genomic Medicine by Kumar, Dhavendra; Eng, Charis;

    Principles and Practice

    Series: Oxford Monographs on Medical Genetics;

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      • Publisher's listprice GBP 255.00
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    115 132 Ft

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    Product details:

    • Edition number 2
    • Publisher OUP USA
    • Date of Publication 13 November 2014

    • ISBN 9780199896028
    • Binding Hardback
    • No. of pages852 pages
    • Size 282x221x43 mm
    • Weight 2223 g
    • Language English
    • 0

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    Short description:

    The first edition of Genomics and Clinical Medicine provided an overview of genomics-based advances in disease susceptibility, diagnosis, and prediction of treatment outcomes in various areas of medicine. Since its publication, the science of genomics has made tremendous progress, and exciting new developments in biotechnology and bioinformatics have created possibilities that were inconceivable only a few years ago. This completely revised second edition of Genomic Medicine reflects the rapidly changing face of applied and translational genomics in the medical and health context and provides a comprehensive coverage of principles of genetics and genomics relevant to the practice of medicine.

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    Long description:

    The first edition of Genomics and Clinical Medicine provided an overview of genomics-based advances in disease susceptibility, diagnosis, and prediction of treatment outcomes in various areas of medicine. Since its publication, the science of genomics has made tremendous progress, and exciting new developments in biotechnology and bioinformatics have created possibilities that were inconceivable only a few years ago. This completely revised second edition of Genomic Medicine reflects the rapidly changing face of applied and translational genomics in the medical and health context and provides a comprehensive coverage of principles of genetics and genomics relevant to the practice of medicine.

    Genomics and Clinical Medicine is the first textbook to comprehensively examine Medicine, especially pathophysiology and pathogenesis, through the lens of genomics.

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    Table of Contents:

    Part I: Principles of Genomic Medicine
    1. Genes, genetics and human genomics- Dhavendra Kumar
    2. The human genome- structure and organization- Andrew P. Read
    3. Human Proteomics- Brian Morrissey, Lisa Staunton, Stephen R Pennington
    4. Epigenetics, Epigenomics and Human Disease- Aravind Ramesh, Cihangir Yandim, Theona Natisvili, Marta Mauri, Piu Pik Law, Jackson P.K. Chan, Santiago Uribe Lewis, Richard Festenstein
    5. Genes, genome and developmental malformations- Dhavendra Kumar
    6. Bioinformatics, Systems Biology and Systems Medicine- Binay Panda and Neeraja M Krishnan
    7. Pharmacogenomics - Critical Component of Genomic Medicine- Wolfgang Sadee
    8. New Drug Development, Drug Response, and Precision Medicines- Michelle Penny and Duncan McHale
    9. Mitochondrial genetics and genomics in clinical medicine- Agnes Rotig and Dhavendra Kumar
    10. Genomics Technology in Clinical Diagnostics- Kevin White
    11. Microbial Genomics: targeted antimicrobial therapy and genome vaccines- Immaculada Margarit & Rino Rappuoli
    12. Nutritional genomics- Zhenglong Gu, Kaixiong Ye and Patrick J. Stover
    13. Genomics in Public and Population Health- Anastasia L. Wise and Teri A. Manolio
    14. Genetic testing and genomic screening- Angus J. Clarke
    15. Biobanking for genomics-based translational medicine- Steven J. Madore
    16. Genetics and Genomics Education: The Path from Helix to Health- Reed E. Pyeritz
    17. Ethical, Legal and Social Issues in Clinical Genomics- Caroline F. Wright, Anna Middleton & Michael Parker
    18. The regulation of human genomics research- Jane Kaye
    Part II: Genomics in Clinical Practice
    19. Genetic and genomic approaches to clinical medicine - Dhavendra Kumar
    20. Genetic and genomic taxonomy of human disease - Dhavendra Kumar
    21. Genomics of complex cardiovascular disease- Foram Ashar and Dan E. Arking
    22. Genomics of type 2 diabetes mellitus and obesity-V. Radha and V. Mohan
    23. Genetics and genomics of osteoporosis and related disorders- Yoshiji Yamada
    24. Genetics and Genomics of chronic kidney disease- Albert C.M.Ong and Alexander P. Maxwell
    25. Genetics and genomics in clinical hematology I- Hemostasis and Thrombosis- John Mcvey
    26. Genetics and genomics in clinical hematology II- Inherited disorders of haemoglobin- David J. Weatherall
    27. Genetics and genomics in clinical hematology III- Acute leukemias- Kenneth Mills
    28. Genetics and Genomics of Chronic Inflammatory disorders I: Inflammatory Bowel Disease- Saad Pathan
    29. Genetics and Genomics of Chronic Inflammatory disorders II: Rheumatoid Arthritis and Related Arthropathies- Kate McAllister and Stephen Eyre
    30. Genetics and Genomics of Chronic Inflammatory disorders III: Bronchial asthma- William Cookson
    31. Genetics and genomics of neuro-psychiatric diseases I: Seizure disorders - William Owen Pickrell
    32. Genetics and genomics of neuro-psychiatric diseases II: Multiple Sclerosis- Katharine Harding and Neil Robertson
    33. Genetics and genomics of neuro-psychiatric diseases III: The Common Dementias- Amy Gerrish, Rebecca Sims and Julie Williams
    34. Genetics and genomics of neuro-psychiatric diseases IV: Schizophrenia and Bipolar Disorder - Jinbo Fan
    35. Genetics and genomics of neuro-psychiatric diseases V: Learning and behavioural disorders- F Lucy Raymond
    36. Clinical Cancer Genomics - Joanne Ngeow and Charis Eng
    37. Genomics and Infectious diseases: Susceptibility, resistance and anti-microbial therapy-Michaela Fakiola, Wei Lu, Sarra E. Jamieson and Christopher S. Peacock
    38. Genomic perspectives of clinical immunology- Cornelius L. Verweij
    39. Genomic applications in Clinical Pediatrics- Vinod Varghese, Sian Morgan and Ian Frayling
    40. Genetics and Genomics in clinical ophthalmology I: The spectrum of genetic eye disease-Graeme CM Black
    41. Genetics and Genomics in clinical ophthalmology II: Glaucoma - Roshanak Sharafieh, Anne H. Child and Mansoor Sarfarazi
    42. Genetics and Genomics in clinical ophthalmology III: Age-Related Macular Degeneration- Mark E. Kleinman and Jayakrishna Ambati
    43. Genomic applications in audiological medicine- Daphne Karfunkel-Doron, Zippora Brownstein and Karen B. Avraham
    44. Genetics and Genomics of skin diseases I: Diseases of the epidermis: eczema, psoriasis- Paul Bowen
    45. Genetics and Genomics of skin diseases II: Genomics of pigmentation and skin cancer- Eugene Healy
    46. The genetic and genomic practice of reproductive medicine- Dhavendra Kumar
    47. Stem cell Genomics - Kyle M. Loh & Bing Lim & Lay Teng Ang
    48. Genomic applications in critical care medicine- Mathew Frise, Charles Hinds & Julian Knight
    49. Targeted molecular therapy- Mark Davies & Julian Sampson
    50. Glossary for genetic and genomic medicine- terms, definitions and phrases- Dhavendra Kumar
    Index

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