Fundamentals of Asymmetric Synthesis
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Product details:
- Edition number 1
- Publisher Routledge
- Date of Publication 1 May 2026
- ISBN 9781032964461
- Binding Paperback
- No. of pages468 pages
- Size 238x175 mm
- Weight 870 g
- Language English 700
Categories
Short description:
Asymmetric synthesis is an integral part of synthetic organic chemistry. Some of the reactions in this book were known prior to 1980, while several new ones, particularly catalytic asymmetric reactions, have been discovered in the recent years.
MoreLong description:
Asymmetric synthesis is an integral part of synthetic organic chemistry. Some of the reactions in this book were known prior to 1980, while several new ones, particularly catalytic asymmetric reactions, have been discovered in the recent years. The impact of this new class of reactions has been impressively extensive—both on organic and medicinal chemistry. These reactions have been accepted whole-heartedly by synthetic organic chemists in developing shorter routes for complex natural targets as well as in the manufacture of a wide range of drug intermediates.
MoreTable of Contents:
Introduction
Terms, Definitions and Concepts in Asymmetric Synthesis
Achiral and Chiral Molecules and Their Properties
Prochirality
Enantioselective and Diastereoselective Synthesis
Methods for Monitoring Enantioselective and Diastereoselective Synthesis
Methods for Inducing Asymmetry
Chiral Substrate Controlled Asymmetric Reactions: Diastereoselection in acyclic systems
Chiral auxiliary controlled asymmetric reactions—Asymmetric a-alkylations
Chiral Stoichiometric Reagent Controlled Asymmetric Synthesis: Chiral Boron Reagents
Chiral Catalyst Mediated Asymmetric Reactions: Enzymes
Chiral Organometallic Catalysed Asymmetric Reactions: Sharpless Asymmetric Epoxidations, Dihydroxylations and Aminohydroxylations
Chiral Organometallic Catalysed Asymmetric Reactions
Organocatalysts in Asymmetric Synthesis—Chiral Additive Mediated Reactions
Asymmetric Aldol Reaction
Asymmetric Diels–Alder reactions
Stereoselective Synthesis and Stereospecific Synthesis
Index
