
From Egg to Embryo
Regional Specification in Early Development
Series: Developmental and Cell Biology Series; 26;
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Estimated delivery time: In stock at the publisher, but not at Prospero's office. Delivery time approx. 3-5 weeks.
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Product details:
- Edition number 2, Revised
- Publisher Cambridge University Press
- Date of Publication 30 May 1991
- ISBN 9780521409438
- Binding Paperback
- No. of pages352 pages
- Size 229x152x18 mm
- Weight 575 g
- Language English 0
Categories
Short description:
Describes our understanding of early animal development and explains how the body plan of an embryo emerges from the newly fertilised egg.
MoreLong description:
The last ten years have shown a dramatic revolution in our understanding of early animal development. This new edition of the successful first edition describes the result of this revolution and explains how the body plan of an embryo emerges from the newly fertilised egg. The book starts with a critical discussion of embryological concepts and explains in simple terms the mathematics of cell states, morphogen gradients and threshold responses. The experimental evidence on the mechanism of regional specification in Xenopus, molluscs, annelids, ascidians as well as Caenorhabditis, the mouse, the chick and Drosophila is then discussed. The whole chapter devoted to the exciting developments in Drosophila provides a clear guide to the subject, including a new table outlining the developmentally important genes. The emphasis throughout is on conceptual clarity and unity: bringing together the mathematical models, embryological experiments and molecular biology into a single, comprehensive coherent account.
"One of the best and clearest explications of the bewildering terminology of embryology that I have ever come across...It would be difficult to find another book where the central facts of early embryonic development are set forth so clearly and economically...Slack establishes himself as an excellent expositor and critic of biomathematical theory." Cell
Table of Contents:
Preface to the second edition; Preface to the first edition; 1. Regional specification in animal development; 2. The concepts of experimental embryology; 3. Theoretical embryology; 4. Hierarchies of developmental decisions; 5. Development with a small cell number; 6. Models for man: the mouse and the chick; 7. The breakthrough; 8. What does it all mean?; Appendix: How to write a program for development; References; Index.
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