From Basic Pain Mechanisms to Headache
Series: Frontiers in Headache Research Series; 14;
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Product details:
- Publisher OUP Oxford
- Date of Publication 23 February 2006
- ISBN 9780198569817
- Binding Hardback
- No. of pages288 pages
- Size 254x176x21 mm
- Weight 651 g
- Language English
- Illustrations Numerous halftones, tables, and line drawings 0
Categories
Short description:
Though the topics of pain and headache are obviously linked, these two research fields have in recent years developed at their own pace, often with scant attention paid to the other. This book brings together researchers and clinicians from the forefront of these two disciplines to explore how the basic pain mechanisms relate to migraine and other forms of headache.
MoreLong description:
Though the topics of 'pain' and 'headache' are obviously linked, these two research fields have in recent years developed at their own pace, often with scant attention paid to the other. By forging closer links between these fields, it should be possible to develop a deeper understanding of both the pain mechanisms associated with headache and a deeper understanding of pain itself. This book brings together researchers and clinicians from the forefront of these two disciplines to explore how the basic pain mechanisms relate to migraine and other forms of headache.
With cutting edge research from the frontiers of headache and pain research, the book will be essential for clinicians treating headache sufferers, providing answers to many of the commonly asked questions about the mechanisms of their headache. It will also be of interest to those pain researchers dealing with mechanisms related to headache and migraine.
Table of Contents:
Section I - Molecular Mechanisms in Inflammatory Pain
Somatostatin and calcitonin gene-related peptide (CGRP) receptors in primary afferent neurons
The capsaicin receptor controls sensitivity and stimulated neuropeptide release in rodent meninges
Cytokines in inflammatory pain
Discussion summary: Molecular mechanisms in inflammatory pain
Section II - Neurobiology of Neuropathic Pain
Mechanisms of inflammatory hyperalgesia
Translation of symptoms and signs into mechanisms in neuropathic pain
Neuropathic pain in the orofacial area
Discussion summary: Neurobiology of neuropathic pain
Section III - The Trigeminal System and Pain
Injury induced neuroplastic changes in trigeminal brainstem subnucleus caudalis: Trigeminal central sensitisation
Vascular and neuronal mechanisms related to the trigeminovascular system
Pathophysiological considerations in trigeminal neuralgia
Parasympathetic activation in experimental trigeminal pain
Trigeminovascular activation in cervicogenic headache
Hypertension-associated hypalgesia: an important mechanism in headache and other pains?
Central projections of sensory innervation of the rat superior sagittal sinus
Discussion summary: the trigeminal system and pain
Section IV - Allodynia and Hyperalgesia
Mechanisms of cutaneous hyperalgesia
Allodynia as a manifestation of migraine and other headaches
Muscular hyperalgesia in the head and orofacial area
Evidence for generalized muscular and cutaneous hyperalgesia in patients with chronic tension-type headache
Migrainous allodynia or triptan-induced allodynia?
Migraine facilitates high frequency of tension-type headache
Clinical assessment of hyperalgesia and allodynia in episodic migraine versus chronic migraine interictally and ictally
Discussion summary: Allodynia and hyperalgesia
Section V - Modulation of Pain
Mechanisms of pain facilitation systems: implications for medication overuse headache
Brainstem mechanisms of ongoing pain
How the brain talks to the spinal cord
Eletriptan in migraine: is pain-free response correlated with pain severity or time from headache onset to dosing?
Efficacy of eletriptan in improving functional impairment in migraine: results using a multidimensional functional and work productivity battery
CNS adverse events in patients treated with triptans: side effect or symptom?
Discussion summary: Modulation of pain
Section VI - Imaging of Pain and Allodynia
Cognitive control of emotion and pain in the human brain
Brain imaging of allodynia and hyperalgesia
Functional neuroimaging of primary headaches
Posterior cerebral hypoperfusion in migraine without aura
Brainstem and hypothalamic activation in spontaneous migraine attacks: a PET study
Discussion summary: Imaging of pain and allodynia
