Free Radicals and Iron
Chemistry, Biology, and Medicine
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Product details:
- Publisher OUP Oxford
- Date of Publication 27 August 1998
- Number of Volumes laminated boards
- ISBN 9780198558927
- Binding Hardback
- No. of pages254 pages
- Size 242x161x19 mm
- Weight 567 g
- Language English
- Illustrations numerous line figures 0
Categories
Short description:
This concise monograph describes a variety of important reactions of iron in biological free-radical reactions. It presents both a chemical and a biochemical perspective of the topic, but at the same time unifies ideas where possible. Iron plays a key role in biological life processes, as a catalayst enabling us to use oxygen to generate the heat and chemical energy that drives life. When iron is not properly controlled within the body it can cause damage by making
free radicals. The authors present a chemical and biomedical perspective of how reactions of iron complexes and free radicals may contribute to human health and disease, especially in reactions of oxygen and hydrogen peroxide.
Long description:
This concise monograph describes a variety of important reactions of iron in biological free-radical reactions. It presents both a chemical and a biochemical perspective of the topic, but at the same time unifies ideas where possible. Iron plays a key role in biological life processes, as a catalayst enabling us to use oxygen to generate the heat and chemical energy that drives life. When iron is not properly controlled within the body it can cause damage by making
free radicals. The authors present a chemical and biomedical perspective of how reactions of iron complexes and free radicals may contribute to human health and disease, especially in reactions of oxygen and hydrogen peroxide.
Table of Contents:
Part 1
A dedication, some history, and a brief overview
Free radicals
Oxygen, hydrogen peroxide, and water
Iron valence states and ligands
The Fenton reaction
Part 2
Natural iron ligands
Protection against superoxide, hydrogen peroxide, and ferrous ions
Superoxide, perioxides, and iron in biological systems
Iron and human diseases
Biological measurements and fingerprints of radical and related damage
Appendix 1 - List of Fenton's publications
Appendix 2 - 'Oxidation of Tartaric Acid in the Presence of Iron'
Appendix 3 - Movement of Electrons and Protons
Appendix 4 - The use of spectroscopic techniques in the detection of free-radical intermediates
Appendix 5 - Reduction Potentials
