Fibrinolytic and Antithrombotic Therapy
Theory, Practice, and Management
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Product details:
- Edition number 2
- Publisher OUP USA
- Date of Publication 27 April 2006
- ISBN 9780195155648
- Binding Paperback
- No. of pages424 pages
- Size 140x208x17 mm
- Weight 482 g
- Language English
- Illustrations Numerous tables and line drawings 0
Categories
Short description:
Thrombotic disorders of the circulatory system represent the leading cause of morbidity, mortality, and health care expenditure in the United States. The Second Edition of Fibrinolytic and Antithrombotic Therapy provides a practical, evidence-based approach to the managment of thrombotic disorders for all clinicians involved in the care of patients with these disorders. It provides not only vital conceptual information on fibrinolytic and antithrombotic therapy, but also the means to apply it to everyday decision making and patient care. Focusing on management guidelines and critical pathways, the text stresses practicality and usability. It will be a valuable resource for the wide range of clinicians involved in the care of patients with these disorders, including cardiologists, emergency physicians, primary care physicians, haematologists, neurologists, intensivists, pharmacists, and nurse practitioners.
MoreLong description:
Thrombotic disorders of the circulatory system represent the leading cause of morbidity, motality, and health care expenditure in the United States. Fibrinolytic and Antithrombotic Therapy provides a practical, evidence-based approach to the management of thrombotic disorders for all clinicians involved in the care of patients with these disorders. It provides not only vital conceptual information on fibrinolytic and antithrombotic therapy, but also the means to apply it to everyday decision making and patient care. Focusing on management guidelines and critical pathways, the text stresses practicality and usability. It will be a valuable resource for the wide range of clinicians involved in the care of patients with these disorders, including cardiologists, emergency physicians, primary care physicians, haematologists, neurologists, intensivists, pharmacists, and nurse practitioners.
The origins of mammalian blood coagulation can be traced back over 400 million years. Despite its long history, it is only within the past century that this complex and pivotal teleologic system has begun to be understood. Most recently, the intricacies of haemostasis and pathologic thrombosis have come to light, leading the way toward new, more effective, and safer treatment modalities.
The Second Edition of Fibrinolytic and Antithrombotic Therapy, even more concise and clinically relevant than the First, provides vital, evidence-based information on management of patients with arterial and venous thrombotic disorders. Since the First Edition, the text has been expanded to cover the evolving topics of atherothrombosis, thrombocardiology, haematologic/thrombophilic conditions, and vascular medicine. It includes up-to-date guidelines for antithrombotic and fibrinolytic therapy, and offers concise summaries of current "standards of care." Chapters are dedicated to discussions of patient-specific therapeutics and to the importance of genomics, proteomics, and metabolomics in defining genotype-phenotype relationships, while throughout the book coagulation, inflammation, and vascular medicine are newly examined as elements in an intricately-linked triad of biochemical and cellular based phenomenology.
This pocket-sized book is full of integrated insights into hemostasis and vital information on fibrinolytic and antithrombotic therapy. The author writes in easy-to-understand language and supplements his text with appropriately placed figures, graphs, tables, EKGs, and algorithms tailored to the needs of practicing clinicians, cardiologists, emergency room physicians, hematologists, and nurses.
Table of Contents:
Part I: Fundamental Scientific Principles
Historical Perspectives of Haemostasis, Coagulation, and Fibrinolysis: A Foundation for Understanding Thrombotic Disorers and Developing Effective Treatment
Vascular Biology, Thromboresistance and Inflammation
Atherosclerosis and Arterial Thrombosis
Venous Thromboembolism
Cardiac Chamber, Aortic and Valvular Thromboembolism
Part II: Fibrinolytics and Platelet Antagonists
Fibrinolytic Agents
Asprin
Clopidogrel
Platelet Glycoprotein llb/llla Receptor Antagonists
Aggrenox and Cilostazol
Novel Platelet Antagonists
Combination Pharmacotherapy
Facilitated Percutaneous Coronary Interventions
Part III: Anticoagulants
Thrombin-Directed Therapy
Factor Xa Inhibitors
Direct Thrombin Inhibitors
Novel Anticoagulants
Part IV: Management of Arterial Thrombotic Disorders
Acute Coronary Syndromes
Peripheral Vascular Disease and Stroke
Valvular Heart Disease and Atrial Fibrillation
Plaque Stabilizing Therapies
Part V: Management of Venous Thrombotic Disorders
Venous Thromboembolism Prophylaxis
Venous Thromboembolism Treatment
Part VI: Genomics, Proteomics and Suspected Thrombophilias
Fundamentals and Patient Evaluation
Part VII: Monitoring Antithrombotic Therapy
Platelet Antagonists
Anticoagulants
Anticoagulation Clinics and Self-Testing
Part VIII: Complications of Treatment and Their Management
Platelet Antagonists
Anticoagulants
Fibrinolytic Agents
Appendixes
A Antithrombotic and Fibrinolytic Agents
B Drug Dosing with Renal Insufficiency
