Fermentation and Biochemical Engineering Handbook
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Product details:
- Edition number 3
- Publisher Elsevier Science
- Date of Publication 30 October 2018
- ISBN 9780128100370
- Binding Paperback
- No. of pages454 pages
- Size 276x215 mm
- Language English 0
Categories
Long description:
A complete reference for fermentation engineers engaged in commercial chemical and pharmaceutical production, Fermentation and Biochemical Engineering Handbook emphasizes the operation, development and design of manufacturing processes that use fermentation, separation and purification techniques. Contributing authors from companies such as Merck, Eli Lilly, Amgen and Bristol-Myers Squibb highlight the practical aspects of the processes-data collection, scale-up parameters, equipment selection, troubleshooting, and more. They also provide relevant perspectives for the different industry sectors utilizing fermentation techniques, including chemical, pharmaceutical, food, and biofuels.
New material in the third edition covers topics relevant to modern recombinant cell fermentation, mammalian cell culture, and biorefinery, ensuring that the book will remain applicable around the globe. It uniquely demonstrates the relationships between the synthetic processes for small molecules such as active ingredients, drugs and chemicals, and the biotechnology of protein, vaccine, hormone, and antibiotic production. This major revision also includes new material on membrane pervaporation technologies for biofuels and nanofiltration, and recent developments in instrumentation such as optical-based dissolved oxygen probes, capacitance-based culture viability probes, and in situ real-time fermentation monitoring with wireless technology. It addresses topical environmental considerations, including the use of new (bio)technologies to treat and utilize waste streams and produce renewable energy from wastewaters. Options for bioremediation are also explained.
MoreTable of Contents:
Part I
Fermentation
1. Fermentation Pilot Plant
2. Mammalian Cell Culture System
3. Bioreactors for Plant Cell Tissue and Organ Cultures
4. Nutritional Requirements in Fermentation Processes
5. Fermentation for Biofuels and Bio-Based Chemicals
Part II
Equipment Design
6. Fermentation Design
7. Agitation
Part III
Recovery
8. Filtration
9. Cross-Flow Filtration
10. Distillation for Recovery of Biofuels and Bio-Based Chemicals
11. Solvent Extraction
12. Evaporation
13. Centrifugation
14. Drying
Part IV
Purification
15. Crystallization
16. Chromatography
Part V
Plant Operations
17. Water Systems for Pharmaceutical Facilities
18. Sterile Formulation
19. Environmental Concerns
20. Instrumentation and Control Systems
21. Statistical Methods for Fermentation Optimization
