Evidence-based ART and Related Treatments by Shibahara, Hiroaki; Morimoto, Yoshiharu; Shiotani, Masahide;

Long description:

This book sheds new light on assisted reproductive technology (ART), providing readers with the latest research and evidence-based practices in this dynamic field. At its core, it addresses critical questions about fertility treatments and their future prospects.

The chapters cover topics such as controlled ovarian stimulation, gamete development, fertilization mechanisms, embryo development, freezing and thawing techniques, implantation processes, preimplantation genetic testing (PGT), and advanced treatments like mitochondrial transfer and uterine transplantation. Readers will find contributions by renowned scholars who delve into these subjects with expert analysis and practical insights.

Designed for physicians involved in ART as well as embryologists, nurses, coordinators, and counselors closely engaged in reproductive medicine, this book offers a comprehensive overview of current evidence-based front-line ART topics. It is an essential resource for understanding both historical advancements and future directions in reproductive technology.

Table of Contents:

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ART and Female Reproductive Endocrinology.- ART and the Reproductive Endocrinology of Males.- Clinical Endocrinology in ART: Controlled Ovarian Stimulation.- Luteal Phase Support in Assisted Reproduction: Advances and Individualized Strategies for Frozen Embryo Transfer”.- Male Gametogenesis.- Gamete Development and Maturation: Oocytes.- Fertilization mechanism.- Fertilization failure and its treatment options”.- Historical development of intracytoplasmic sperm injection (ICSI) using animal models.- Various ICSI Methods.- Fertilization failure by ICSI.- Culture Medium of Embryo Development.- Time-lapse Cinematography of Embryo Development.- Freeze and Thaw: Sperm.- Cryopreservation of Testicular Cells and Tissue.- Freeze and Thaw: Oocyte.- Cryopreservation of human embryos/blastocysts.- Current Status of Ovarian Tissue Cryopreservation in Childhood, Adolescent, and Young Adult Cancer Patients.- Mechanism of Implantation: Coordinated Roles of COX1/COX2–Prostaglandin and LIF–STAT3 Pathways.- Preimplantation Genetic Testing for Aneuploidy (PGT-A): Efficacy, Controversies, and Clinical Implications.- Preimplantation Genetic Testing: PGT-SR.- Preimplantation Genetic Testing: PGT-M.- Uterine Microbiome in Reproductive Medicine.- Chronic Endometritis.- The Current Status and Future Challenges of Falloposcopic Tuboplasty.- Uterus Transplantation: Clinical Advances and Future Perspectives.- TESE as advanced treatment.- Alternative treatments as Advanced Treatments.- Mitochondria Transfer as Advanced Treatments.- Application of Platelet-Rich Plasma (PRP), a Regenerative Medicine, in Assisted Reproductive Technology.- PFC-FD as Advanced Treatments.- IVM as Advanced Treatment.- New method of embryo transfer as Advanced Treatments.- Tacrolimus treatment for women with repeated implantation failures and recurrent pregnancy losses.- Improving Pregnancy Rates through the Use of Artificial Intelligence (AI) in IVF Laboratories.- AI-based birth prediction using embryo images and clinical data. Current status and future perspectives.