Eukaryotic Transcription Factors
Series: Biomedical Engineering;
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33 066 Ft (31 491 Ft + 5% VAT)
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33 066 Ft
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Product details:
- Edition number 4
- Publisher Academic Press
- Date of Publication 21 November 2003
- ISBN 9780124371781
- Binding Hardback
- No. of pages384 pages
- Size 246x188 mm
- Weight 1070 g
- Language English 0
Categories
Long description:
Now in two-colour throughout, the fourth edition of Eukaryotic Transcription Factors has been completely rewritten and restructured to take into account the tremendous advances in our understanding of transcription factors and the mechanisms by which they act. Considerable emphasis has been given to the interaction between transcription factors and chromatin structure. Also included is an entirely new section on the mediator complex and expansion of the space devoted to co-activators and co-repressors.This book is essential reading for all those who wish to understand the impact of molecular biology on medicine, whatever their speciality.
MoreTable of Contents:
DNA sequences, transcription factors and chromatin structureThe importance of transcriptionChromatin structure and its remodelling Chromatin structure and gene regulationChromatin remodelling factorsHistone acetylationDNA sequence elementsThe gene promoterSequences involved in the basic process of transcription Sequences involved in regulated transcriptionSequences which act at a distanceNegatively acting DNA sequencesInteraction between factors bound at various sitesConclusionsReferencesMethods for studying transcription factorsIntroductionMethods for studying DNA-protein interactionsDNA mobility shift assayDNaseI footprinting assayMethylation interference assayIn vivo Footprinting assayMethods for purifying and/or cloning transcription factorsProtein purificationGene cloningUse of cloned genesDomain mapping of transcription factorsDetermining the DNA binding specificity of an uncharacterised factorIdentification of target genes for transcription factors
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