Escourolle and Poirier's Manual of Basic Neuropathology
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Estimated delivery time: Expected time of arrival: end of January 2026.
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Product details:
- Edition number 7
- Publisher OUP USA
- Date of Publication 19 August 2028
- ISBN 9780197661307
- Binding Paperback
- No. of pages486 pages
- Size 253x179x24 mm
- Weight 998 g
- Language English 0
Categories
Short description:
This manual provides a brief summary of disorders of the nervous system, or “brain”. The nervous system is critical for all sensations and movements, as well as memory and cognition, providing the basis for the human interactions with the environment. The Manual covers all of these disorders, with separate chapters on each major category of disease. Alzheimer disease with impairment of memory and cognition, and Parkinson disease with its prominent movement disorder symptoms, are discussed as forms of neurodegeneration. Head injuries and the long-term consequences of repeated head trauma, such as that seen in boxers and football players, are discussed as brain trauma. Tumors, including glioblastoma, are summarized with the newest classification arising from the World Health Organization's 2021 classification system.
MoreLong description:
Escourolle and Poirier's Manual of Basic Neuropathology has a long-standing tradition of providing complete and concise descriptions of the principal diseases of the nervous system, limiting clinicopathological correlations and pathophysiological considerations to the essential principles. With a target audience of professionals hoping to gain their first detailed understanding of the pathology underlying neurologic disease, the manual assumes that the reader has familiarity with the basic concepts of neuroanatomy, histology and general principles of pathology, as well as the basic principles of clinical neurology. As a result, the manual has been very popular with physicians wanting a brief introductory text, including residents in pathology, neurology, neurosurgery, and psychiatry. The Manual is also popular with staff pathologists and neurologists, neuroscientists, and even some medical students with interests in clinical neurosciences.
In the face of remarkable advances in basic neuroscience, molecular biology, and genetics, which are fields of research that have direct impact on neuropathology, the seventh edition provides a critical update that incorporates the most recent molecular definitions. The Manual does not emphasize radiological images, as this information is available elsewhere. Rather, it describes the pathologic characteristics of neurologic disease, with extensive macroscopic illustrations and whole-brain sections. Progress in molecular biology and genetics has revolutionized the laboratory diagnosis of many groups of neurological diseases. The classification of neurologic disease often includes molecular markers, and as a result, the content of molecular and genetic data is included whenever it is required for neuropathological classification.
The seventh edition now includes immunohistochemical in situ identification of abnormal proteins, or abnormal distribution of proteins in neuropathology. Gene sequencing or mutated constructs permits the identification of specific gene mutations and has led to considerable advances in the understanding and classification of degenerative, neoplastic and developmental diseases. In fact, molecular and genetic data are now a crucial component of the defining criteria for the diagnosis and classification of intracranial tumors, data that is essential for the neuro-oncologist, neurosurgeon, and radiation therapist to determine prognosis and optimal personalized treatments. The classification of brain tumors has also been updated by the World Health Organization in 2021.
Genetic data have also completely changed the understanding, classification and diagnosis of hereditary metabolic disorders, as well as many classes of myopathies and neuropathies. Newly emerging diseases in the Seventh Edition include chronic traumatic encephalopathy associated with repeated head trauma, late-onset cognitive disorders including PART and LATE, and new viral syndromes including COVID and Zika virus. Throughout, the Manual draws on a world-wide expertise, with authors from four continents collaborating to provide a remarkable breadth of experience.
despite having the word "basic" in the title, this book covers complex topics with ease. For neuropathologists who encounter a topic outside of their area of expertise, this book provides an easy reference and a starting point for further research. It is an essential book for trainees, neuropathologists, and any general pathologists or clinicians with an interest in neuropathology.
Table of Contents:
Foreword by Allan H. Ropper
Preface to Seventh Edition
Contributors List
Chapter 1: Basic Pathology of the Nervous System
Danielle Seilhean, Matthew Torre, Gabor G. Kovacs, and Umberto De Girolami
Chapter 2: Tumors of the Central Nervous System
Franck Bielle, Sandro Santagata, and Keith L. Ligon
Chapter 3: Central Nervous System Trauma
Colin Smith and R. Ross Reichard
Chapter 4: Vascular Disease
Jean-Jacques Hauw, Harry V. Vinters, Pierre Amarenco, and Umberto De Girolami
Chapter 5: Infections of the Central Nervous System
Fabrice Chrétien, Isaac Solomon, Leila Chimelli, and Leroy R. Sharer
Chapter 6: Human Prion Diseases
Markus Glatzel and Stéphane Haik
Chapter 7: Multiple Sclerosis and Related Inflammatory Demyelinating Diseases
Hans Lassman and Danielle Seilhean
Chapter 8: Pathology of Degenerative Diseases of the Nervous System
Yuichi Riku, Susana Boluda, Mel B. Feany, and Toshiki Uchihara
Chapter 9: Acquired Metabolic Disorders
Michael Punsoni, Luciano Neder, Isabelle Plu, and Douglas Anthony
Chapter 10: Hereditary Metabolic Disease
Douglas C. Anthony, Yann Nadjar, and Hans H. Goebel
Chapter 11: Congenital Malformations and Perinatal Diseases
Homa Adle-Biassette, Brian Harding, and Jeffrey A. Golden
Chapter 12: Pathology of Skeletal Muscle
Teresinha Evangelista, Anthony A. Amato, Basil T. Darras, and Umberto De Girolami
Chapter 13: Pathology of Peripheral Neuropathy
Jean-Michel Vallat, Douglas C. Anthony, Anthony Amato, and Umberto De Girolami
Chapter 14: Diseases of the Pituitary Gland
Sandro Santagata, David Meredith, Chiara Villa, and Vânia Nosé
Appendix: Brief Survey of Neuropathology Techniques
David Meredith and Franck Bielle
