Dialysis Amyloid
Series: Oxford Clinical Nephrology Series;
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Product details:
- Publisher OUP Oxford
- Date of Publication 7 March 1996
- ISBN 9780192624949
- Binding Hardback
- No. of pages290 pages
- Size 247x173x22 mm
- Weight 720 g
- Language English
- Illustrations black and white photographs, line figures and tables 0
Categories
Short description:
Amyloidosis is a serious condition associated with renal dialysis, leading to progressive organ failure, and is of great concern to all clinical nephrologists. It is particularly common in countries where renal transplantation is rare, such as Japan. This book is aimed at practising nephrologists and will help them successfully to diagnose, relieve, and possibly prevent dialysis-related amyloidosis.
MoreLong description:
Dialysis amyloidosis is a syndrome observed in dialysis patients characterized initially by joint pain, followed later by joint destruction. It is at present one of the few compliations in these patients.
The factors involved in the genesis of this syndrome are not yet known with certainty and there is as yet no proven efficacious treatment otehr then renal transplantation. As a result, the interest in this topic among nephrologists remains very high.
Dialysis amyloid gives general information on the pathophysiology, and the clinical aspects of all types of amyloidosis. It then goes on to discuss recently discovered B2, type of dialysis amyloidosis, from clinical and pathological features to physiological and pathophysiological aspects of this serious complication which effects patients suffering from chronic renal failure.
This book will give nephrologists and rheumatologists a clear understanding of the dialysis amyloidosis syndrome as well as making a valuable contribution to identifying strategies for treatment and prevention.
this book achieves a balance between clinical topics which will appeal to all practising nephrologists, and more fundamental aspects of amyloidosis which will interest anyone trying to unravel this challenging disorder.
Table of Contents:
Part I: General aspects of amyloidosios
Pathpophysiology of amyloidogenesis
Various clinical types of amyloidosis
Part II: Clinical characteristics of *B2=microglobulin amyloidosis
Arthropathy and carpal tunnel syndrome of *B2-microglobulin amyloidosis
Radiology of dialysis amyloidosis
Ultrasonography of the joints
Whole-body scintigraphy
Part III: Pathology of *B2-microglobulin deposits
Composition of *B2-microglobulin deposits
Description, localization, and progression of B2-microglobulin dialysis-related amyloid deposition
Part IV: Physiopathology of *B2-microglobulin accumulation and deposition
Characteristics of *B2-microglobulin metabolism
Involvement of *B2- microglobulin modified with AGEs in dialysis-related amyloidosis
Factors modifying removal and production of *B2-microglobulin
Determinants of fibril precipitation and aggregation in amyloid deposits.
Part IV: Review of the clinical evidence on the prophylactic and therapeutic approaches to *B2-microglobulin amyloidosis
Prevention and treatment of *B2-microglobulin amyloidosis
