Creating Modern Neuroscience: The Revolutionary 1950s
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Product details:
- Publisher OUP USA
- Date of Publication 12 November 2009
- Number of Volumes BB
- ISBN 9780195391503
- Binding Hardback
- No. of pages304 pages
- Size 152x236x22 mm
- Weight 635 g
- Language English
- Illustrations 32pp plates inserts between 148p and 149p 0
Categories
Long description:
For modern scientists, history often starts with last week's journals and is regarded as largely a quaint interest compared with the advances of today. However, this book makes the case that, measured by major advances, the greatest decade in the history of brain studies was mid-twentieth century, especially the 1950s. The first to focus on worldwide contributions in this period, the book ranges through dozens of astonishing discoveries at all levels of the brain, from DNA (Watson and Crick), through growth factors (Hamburger and Levi-Montalcini), excitability (Hodgkin and Huxley), synapses (Katz and Eccles), dopamine and Parkinson's (Carlsson), visual processing (Hartline and Kuffler), the cortical column (Mountcastle), reticular activating system (Morruzzi and Magoun) and REM sleep (Aserinsky), to stress (Selye), learning (Hebb) and memory (HM and Milner). The clinical fields are also covered, from Cushing and Penfield, psychosurgery and brain energy metabolism (Kety), to most of the major psychoactive drugs in use today (beginning with Delay and Deniker), and much more.
The material has been the basis for a highly successful advanced undergraduate and graduate course at Yale, with the classic papers organized and accessible on the web. There is interest for a wide range of readers, academic, and lay because there is a focus on the creative process itself, on understanding how the combination of unique personalities, innovative hypotheses, and new methods led to the advances. Insight is given into this process through describing the struggles between male and female, student and mentor, academic and private sector, and the roles of chance and persistence. The book thus provides a new multidisciplinary understanding of the revolution that created the modern field of neuroscience and set the bar for judging current and future advances.
Table of Contents:
Preface
Introduction: Why Study History? Why the 1940s and the 1950s?
Genes: Starting with DNA
Signaling Molecules: The First Growth Factor
The First Neurotransmitters in the Brain
Cell Biology and the Synapse
Physiology: The Action Potential
Phsyiology: Synaptic Potentials and Receptor Potentials
Functional Organization of Neurons and Dendrites
Neural Circuits: Spinal Cord, Retina, Invertebrate Systems
Neural Circuits: Cortical Columns and Cortical Processing
Neural Systems: The Neural Basis of Behavior
Learning and Memory: Donald Hebb, Brenda Milner, and HM
Neurology: Foundations of Brain Imaging
Neurosurgery: From Cushing to Penfield
Neuropsychiatry: The Breakthrough in Psychopharmacology
Theoretical Neuroscience: The Brain as a Computer and the Computer as a Brain
References
Links
Notes
Index