Clinical Trials in Cancer
Principles and Practice
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101 220 Ft
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Product details:
- Publisher OUP Oxford
- Date of Publication 10 April 2003
- ISBN 9780192629593
- Binding Hardback
- No. of pages386 pages
- Size 247x173x26 mm
- Weight 788 g
- Language English
- Illustrations numerous tables and line figures 0
Categories
Short description:
Studies to evaluate new cancer treatments must be very carefully designed, conducted, analysed and interpreted to ensure that both effective and ineffective treatments, and their short and longer-term effects, are identified at as early a stage as possible. This book provides a practical, step-by-step guide on how to design, conduct and analyse clinical trials in cancer patients, written by researchers with considerable experience of working day-to-day on cancer trials and related research activities.
MoreLong description:
Clinical Trials in Cancer provides concise, accessible and practical information on the practicalities of planning, designing, conducting, analysing, reporting, and interpreting phase III clinical trials predominantly, but also single-arm and randomized phase II trials. The book shows clearly how recent developments and current thinking can be implemented. Information on the need to decide and measure realistic target differences in trials, the conduct and interpretation of interim analyses, patient advocacy, good clinical practice, the study of quality of life, the role of meta-analyses, and informed consent and other ethical issues are also covered.
This book will prove invaluable for medical, statistical, and biological cancer researchers, health care professionals, and researchers in the pharmaceutical industry. Trial sponsors, principal investigators, members of data monitoring and trial supervisory committees, specialists invited to provide independent assessments, and many others involved in all aspects of research related to clinical trials should also find this book helpful.
. . . excellent self-referencing . . . I would unequivocally recommend this book to those new to running clinical trials and to those with some experience. It is both very readable and also likely to be of use as a reference text.
Table of Contents:
Introduction
The public perspective
What type of trial is needed?
Design issues for randomised trials
Trial size
Quality of life in clinical trials
Putting plans into practice
Conducting trials
Analysis
Reporting and interpreting results
Systematic reviews and meta-analysis
Benefits of an established trials centre and research group
