Product details:

ISBN13:9781774915660
ISBN10:1774915669
Binding:Hardback
No. of pages:322 pages
Size:229x152 mm
Weight:1660 g
Language:English
Illustrations: 10 Illustrations, black & white; 19 Illustrations, color; 19 Tables, black & white
685
Category:

Cervical Cancer

Signaling Pathways, Molecular Mechanisms, Natural Products, and Therapeutic Approaches
 
Edition number: 1
Publisher: Apple Academic Press
Date of Publication:
 
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Publisher's listprice:
GBP 150.00
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Short description:

Focuses on new approaches to one of the major cancers of the female reproductive system?cervical cancer. Expounds on the idea that, modulation in various signaling pathways is responsible for cervical cancer pathogenesis, and inhibition of these crucial pathways could be a better therapeutic approach for cervical cancer management.

Long description:

There has been a tremendous advancement in cancer therapeutics, and this book focuses on new approaches to one of the major cancers of the female reproductive system?cervical cancer. Cervical cancer is the fourth most frequent cancer in women worldwide and, especially, a foremost cause of morbidity in women in developing countries, including India. Several research findings have suggested that modulation in various signaling pathways is responsible for cervical cancer pathogenesis, and inhibition of these crucial pathways could be a better therapeutic approach for cervical cancer management. This book expounds on this approach, providing a detailed insight of the deregulated oncogenic signaling pathways involved in the progression of cervical cancer.


The key topics covered within this book include



  • Signaling pathways involved in cervical cancer

  • Mechanisms behind the involvement of these aberrant signaling pathways

  • Cell signaling pathways and their alterations in cancer

  • Molecular biology behind cervical cancer

  • Drug development approaches for the management of cervical cancer

  • Cervical cancer therapeutics and the possible aspects, including progression and inhibition using natural products and synthetic approaches

Oncologists, cancer scientists, and research professionals will benefit from this volume, which provides a single platform that presents new research on the pathways responsible for the progression of cervical cancer so that they, in turn, can design their research work effectively and can discover novel innovations in the field of cancer therapeutics.



"An up-to-date view of the epidemiology related to cervical cancer. . . . An extremely valuable tool for students, researchers, and even health professionals who wish to design their future research studies, promote the continuous development of the area, and even contribute to a marked progress in the area of oncology, insofar as some signaling pathways identified here may contribute to a deepening of knowledge and innovation in other sub-areas of oncology."


?From the Foreword by Natália Cruz-Martins, PhD, Faculty of Medicine, University of Porto, Portugal

Table of Contents:

Foreword by Natália Cruz-Martins, PhD, Faculty of Medicine, University of Porto, Portugal 1. Cervical Cancer: Global Incidences and Progression 2. Wnt Signalling Pathway in Cervical Cancer 3. TLR Signalling Pathway in Cervical Cancer 4. PI3K-Akt-Mtor Signalling Pathways 5. Notch Signalling Pathway 6. Apoptotic Pathways in Cervical Cancer Management 7. NF-Kb in Cervical Cancer Management 8. JAK-STAT Pathway in Cervical Cancer Management 9. Role of Micro-RNA in Cervical Cancer Progression and Its Therapeutic Implications 10. Cervical Cancer and Natural Products: Anticancer Potential and Mode of Action 11. Therapeutic Approaches for Cervical Cancer Management