Bioresources for Managing and Treating Dementia by Asuku, Abraham Olufemi; Ajibare, Ayodeji Johnson; Olaniyan, Olugbemi Tope;

Short description:

Dementia is a health challenge with remarkable socio-economic implications. In spite of advances in conventional treatment, there is an urgent need for more accessible and effective therapies. This book explores the potential of bioresources in dementia management, focusing on their mechanisms of action and addressing critical obstacles.

Long description:

Globally, dementia is a health challenge with remarkable socio-economic implications. In spite of advances in conventional treatment, there is an urgent need for more accessible, effective, and safer therapeutic options. Bioresources—including microbial metabolites, medicinal plants, and marine-derived compounds—offer a promising avenue for dementia treatment and management. Phytochemicals like terpenoids, flavonoids, and alkaloids have shown neuroprotective properties, like anti-inflammatory, antioxidative, and cholinesterase-inhibitory effects. An overview of the potential of various bioresources in dementia treatment and management is discussed in this book. However, the translation of bioresource-based therapies into clinical practice faces several obstacles. Limitations are variability in low bioavailability, concentrations of bioactive compounds, problems with regulations, and the need for rigorous clinical validation. Surmounting these obstacles entails advanced biotechnological approaches, interdisciplinary collaboration, and supportive policy frameworks. This book explores the potential of bioresources in dementia management, focusing on their mechanisms of action and key prospects and addressing the critical obstacles that must be navigated to harness their full therapeutic potentials.

     • Discusses pathophysiology and prevalence of dementia as well as the significance of the applications of diverse bioresources for managing and treating dementia

     • Highlights the application of medicinal plants, phytochemicals, microbial products, and marine-derived bioproducts for the management and treatment of dementia, with emphasis on their mechanisms of action

     • Discusses challenges, considerations, and future directions on the use of bioresources for managing and treating dementia

This book is ideal for clinicians, biotechnologists, biomedical scientists, dementia caregivers, researchers, and academicians. 

Table of Contents:

1. Dementia: Pathophysiology, Types, and Global Prevalence 2. Pharmacotherapies of Dementia and Their Limitations 3. Bioresources: Global Regulatory Bodies and Agencies 4. Ginkgo biloba for Managing and Treating Dementia 5. Bacopa monnieri for Managing and Treating Dementia 6. Curcumin for Managing and Treating Dementia 7. Huperzine A for Managing and Treating Dementia 8. Withania somnifera for Managing and Treating Dementia 9. Ocimum gratissimum for Managing and Treating Dementia 10. Green Tea for Managing and Treating Dementia 11. 6-Gingerol for Managing and Treating Dementia 12. Quercetin for Managing and Treating Dementia 13. Lion’s Mane for Managing and Treating Dementia 14. Ganoderma lucidum for Managing and Treating Dementia 15. Fucoidan for Managing and Treating Dementia 16. Docohexanoic Acids (from Fish and Algae) for Managing and Treating Dementia 17. Chitosan for Managing and Treating Dementia 18. Challenges and Future Perspectives on the Applications of Bioresources for Managing and Treating Dementia