Biological evaluation of some 2,5-disubstituted-1,3,4-oxadiazoles
Synthesis, Biological evaluation of some novel 2,5-Disubstituted-1,3,4-Oxadiazoles containing furan moiety
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Product details:
- Edition number Aufl.
- Publisher LAP Lambert Academic Publishing
- Date of Publication 1 January 2011
- Number of Volumes .
- ISBN 9783846553572
- Binding Paperback
- No. of pages60 pages
- Language English 0
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Long description:
2-5-disubstituted 1,3,4-oxadiazoles constitute a unique class of nitrogen and oxygen containing 5-membered hetero cycles. During the past years considerable evidence also accumulate to demonstrate the efficacy of 1,3,4-oxadiazoles including anti-malarial, anti-bacterial, anti-inflammatory and other biological activities. In an attempt for the enhancement of biological activity incorporation of 1,3,4-oxadiazoles was made with furan moiety. The main objective was to synthesize various 2,5-disubstituted-1,3,4-oxadiazoles, which were characterized by different spectroscopic techniques (IR,NMR,MASS). Analysis of spectral data of all the compounds revealed the successful formation of Different derivatives derived from 2,5-disubstituted-1,3,4-oxadiazoles and antibacterial and anti-inflammatory activities were evaluated.
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