Product details:

ISBN13:9780443160134
ISBN10:0443160139
Binding:Paperback
No. of pages:580 pages
Size:235x191 mm
Weight:450 g
Language:English
699
Category:

Biochemical and Molecular Pharmacology in Drug Discovery

 
Publisher: Elsevier
Date of Publication:
 
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Long description:

Biochemical and Molecular Pharmacology in Drug Discovery comprises fundamental biochemical and molecular aspects of drug discovery and basic understanding of modern drug discovery approaches, along with certain key topics related to molecular pharmacology of drugs and therapeutics. The book explains the phenomena of drug-target interactions, considering different biochemical systems and cellular strategies. With the advent of technologies, current advances, and research trends move toward molecular and/or target-based drug design and discovery. Through this book, readers will gain skills and knowledge with a thorough understanding of the subject of biochemical and molecular pharmacology in a comprehensive and systematic manner. Molecular pharmacology has gained significant momentum among researchers, scientists, and academicians because of its increasing interest in drug discovery research across the globe. Molecular pharmacology involves a fundamental understanding of drug actions at the molecular level with the help of several tools and techniques of biochemical and molecular biology.




  • Highlights the fundamentals of biochemical and molecular aspects, with reference to drug discovery research
  • Depicts modern drug discovery approaches such as reverse pharmacology, drug repositioning, and CADD in the context of current research updates
  • Summarizes recent developments in the molecular pharmacology of novel drugs/ therapeutic molecules
Table of Contents:
1. Structure and Functions of Biomolecules
2. Pharmacokinetics and Pharmacodynamics
3. Overview of Drugs and Drug Targets
4. Nucleic Acids as Drug Targets
5. Molecular Cloning of Drug Targets
6. Pharmacogenetics and pharmacogenomics in drug discovery
7. Drug-Receptor Interactions
8. Enzymology in Drug Discovery
9. Targeting Epitranscriptomics for Novel Drug Development
10. Applications of molecular pharmacology in drug discovery
11. Fundamentals of drug design and discovery
12. Fundamental Approaches of Drug Discovery
13. Enzyme Inhibitors: Design of Kinase Inhibitors as anticancer drugs
14. Reverse Pharmacology and Drug Repositioning in Drug Discovery
15. Bioinformatics and CADD Approaches in Drug Discovery
16. Artificial Intelligence-based protein structure prediction and systems biology-guided smart drug screening
17. Recombinant DNA Technology and Gene Therapy
18. Gut-Health Pharmacology: Integrating Microbiota Insights with Natural Product Therapies
19. Neuropharmacology and Neurotherapeutics: Advancing the Understanding and Treatment of Neurological Disorders
20. Molecular Oncobiology and Cancer Chemotherapeutics
21. Molecular Inflammopharmacology and Therapeutics
22. Molecular Cardiopharmacology and Therapeutics-I
23. Molecular Cardiopharmacology and Therapeutics-II
24. Molecular Endocrine Pharmacology and Therapeutics
25. Molecular Viral Infections and Anti-viral Therapeutics