Alternative Splicing and Cancer
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Product details:
- Edition number 1
- Publisher CRC Press
- Date of Publication 30 July 2025
- ISBN 9781032196985
- Binding Paperback
- No. of pages210 pages
- Size 234x156 mm
- Language English
- Illustrations 37 Illustrations, black & white; 15 Illustrations, color; 16 Halftones, black & white; 6 Halftones, color; 21 Line drawings, black & white; 9 Line drawings, color; 16 Tables, black & white 700
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Short description:
This book "Alternative Splicing and Cancer" explores the crucial role alternative splicing, a post-transcriptional process, plays in human health and diseases, particularly cancer.
MoreLong description:
This book Alternative Splicing and Cancer explores the crucial role alternative splicing, a post-transcriptional process, plays in human health and diseases, particularly cancer. Diving deep into the complexities of gene expression and protein diversity, the book illuminates how abnormal splicing contributes to aggressive tumor formation, affecting cellular functions such as proliferation, survival, and immune evasion. With a focus on understanding molecular mechanisms, this book unravels potential diagnostic and prognostic targets, opening doors for enhanced anti-cancer treatment efficacy. An indispensable resource for anyone intrigued by the interplay between gene splicing and cancer biology, it paves the way towards innovative therapeutic strategies.
MoreTable of Contents:
Preface 1. Alternative Splicing and Human Diseases 2. Mechanism of RNA Splicing 3. Alternative Splicing: A New Cancer Hallmark 4. Deregulated Spliceosome and Splice Variants in Cancers 5. Deregulated Oncogenic Signaling Pathway(s) and Alternative Splicing 6. Alternative Splicing and Metastasis 7. Role of Splice Variant of Pyruvate Kinase M2 (PKM2) in Cancer Metabolism 8. Alternative Splicing and Immune Surveillance 9. Therapeutic Targeting of Alternative Splicing in Cancers 10. Alternative Splicing in Cancer Drug Resistance 10. A Systematic Evaluation of Alternative Splicing and Cancer: A Review Index.
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