AIDS at a Crossroads
How Antiretrovirals and Community Transformed the HIV Response
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Product details:
- Publisher OUP Oxford
- Date of Publication 30 July 2026
- ISBN 9780198837015
- Binding Paperback
- No. of pages336 pages
- Size 246x171 mm
- Language English 700
Categories
Short description:
Building upon the early history of the HIV pandemic laid out in the 2008 book A Decade of HAART, this book explores the scientific breakthroughs and global response to the HIV pandemic from the mid-1990s through 2023.
MoreLong description:
AIDS at a Crossroads: How Antiretrovirals and Community Transformed the HIV Response chronicles the global HIV response through 2023, and the remarkable progress achieved toward epidemic control through innovation in biomedicine, the resolve of political leadership, and the steadfast commitment of communities on the frontlines of the HIV response. In this sequel to A Decade of HAART: The Development and Global Impact of Highly Active Antiretroviral Therapy (2008), leading voices in HIV medicine and global health chronicle how innovation in biomedicine, political will, and community leadership together transformed the trajectory of the HIV pandemic.
This timely volume captures the extraordinary progress toward epidemic control achieved through antiretroviral therapy, pre-exposure prophylaxis, and the validation of treatment as prevention, while candidly assessing the stigma, inequities, and policy failures that persist. Written during the COVID-19 pandemic, the book includes initial insights into the colliding pandemic's shock on health systems and how this novel public health threat tested the resilience of HIV responses everywhere. New political and fiscal shocks in 2025 - precipitated by the Trump administration's HIV and global health policy reversals and funding cuts - now threaten this progress in the United States and beyond.
Divided into three sections spanning biomedical innovation, country case studies, and strategies for achieving the goal of ending AIDS as a public health threat, AIDS at a Crossroads offers historical reflection on a public health success yet to be attained and an urgent warning that controlling, eliminating, and ultimately eradicating the HIV pandemic will depend as much on scientific breakthroughs as on sustained political will and community leadership.
Table of Contents:
Part 1. ART, PrEP, and the Continuum from Despair to a Decade of Action
How Antiretroviral Therapy Turned the Tide of the HIV Pandemic
HPTN 052, the PARTNER Study, and the Dawn of Treatment as Prevention
The Impact of Option B+ PMTCT Implementation on Mothers Living with HIV
Challenges and Successes from a Decade and a Half of HIV Antiretroviral Therapy
Pre-Exposure Prophylaxis for the Biomedical Prevention of HIV Infection
Molecular Genetics: Using Phylogenetics to Enhance the HIV Response
From Elimination to Eradication: The Role of an HIV Vaccine and/or Cure
Part 2. Action to Impact: Country Experiences with ART and PrEP Scale-Up
Country Review: Kenya
Country Review: South Africa
Country Review: Uganda
Country Review: Australia
Country Review: China
Country Review: Thailand
Country Review: Brazil
Country Review: Haiti
Country Review: Argentina
Country Review: United States
Country Review: The Netherlands
Country Review: Spain
Part 3. Challenges and Opportunities for Ending AIDS as a Public Health Threat
A Revitalized Human Rights and Legal Framework for Ending AIDS
Financing the AIDS Response: Bilateral, Multilateral, and National Investments
Political Leadership for HIV Control: It Is Time to Unite for Action
Urbanizing Global Goals by Accelerating HIV Responses in Fast-Track Cities
Leveraging the HIV Response for the Achievement of Universal Health Coverage
Conclusion