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  • A Decade of HAART: The Development and Global Impact of Highly Active Antiretroviral Therapy

    A Decade of HAART by Zuniga, José M; Whiteside, Alan; Ghaziani, Amin;

    The Development and Global Impact of Highly Active Antiretroviral Therapy

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      • Publisher's listprice GBP 165.00
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    Product details:

    • Edition number and title sociologists
    • Publisher OUP Oxford
    • Date of Publication 28 August 2008

    • ISBN 9780199225859
    • Binding Hardback
    • No. of pages546 pages
    • Size 254x177x33 mm
    • Weight 1086 g
    • Language English
    • Illustrations 75 black and white line illustrations
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    Short description:

    Highly active antiretroviral therapy (HAART) is a therapeutic intervention developed by clinicians and researchers in order to fight the HIV pandemic. This book marks the tenth anniversary of HAART, and reviews both the achievements to date, and an exploration of the challenges that may arise in the future.

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    Long description:

    Highly active antiretroviral therapy (HAART) is a therapeutic intervention developed by clinicians and researchers in order to fight the HIV pandemic. It has contributed to a significant reduction in AIDS-related mortality and allowed many previously bed-ridden patients to live healthier, more productive lives. Until the advent of HAART in 1996, a diagnosis of HIV infection was considered a death sentence. A decade later, the disease has been transformed into a serious, yet potentially manageable, medical condition for thousands of people living with HIV/AIDS in the developed world - almost overnight creating a generation of "HIV Survivors" - and forged a global movement to ensure that its Lazarus-like benefit reaches millions more in the developing world.

    This book reviews the achievements of HAART over the past decade, and explores the challenges that may arise in the future. It recounts key landmarks in the development and introduction of HAART from the perspective of clinicians, researchers, economists, sociologists, and public policy experts, including the co-discoverers of HIV, Luc Montagnier and Robert Gallo. It explores the evolution of the disease, the evolution of HIV treatment, and the economic, social, and public policy impacts of both HIV and the introduction of HAART.

    ...an excellent book...of interest both to those with an existing knowledge and interest in HIV as well as those who have come to the subject more recently...provides a unique insight into the dramatic period surrounding the introduction of HAART and thoughtful insights into likely future developments.

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    Table of Contents:

    Foreword
    Introduction
    A Decade of HAART: Trials, Tribulations, and Successes
    A world ravaged by a disease without HAART
    Turning the world on its ear: defining milestones on the road to HAART
    Outcome and impact of 10 years of HAART
    Highly Active Anti-Retroviral Therapy in HIV-infected children: a decade later
    HAART in High Human Development Countries
    Country review: Australia
    Country review: Chile
    Country review: Germany
    Country review: Italy
    Country review: United States of America
    The HIV Outpatient Study (HOPS) and the Multicenter AIDS Cohort Study
    The French Hospital Database on HIV (FHDH) ANRS CO.4
    EuroSIDA: A prospective observational study of chronic HIV infection 13-1 Across the European continent
    The Swiss HIV Cohort (SHCS)
    The OPTIMA Cohort
    HAART in Medium Human Development Countries
    Country review: Brazil
    Country review: China
    Country review: South Africa
    Country review: Thailand
    Cohort studies in Brazil: Projet Praça Onze
    The HIV Netherlands-Australia-Thailand research collaboration (HIVNAT)
    HAART in Low Human Development Countries
    Country review: Haiti
    Country review: Malawi
    Country review: Senegal
    Country review: Zambia
    Future Challenges in the Next Decade of HAART
    Clinical challenges of lifetime HAART
    Maintaining and developing health systems to sustain HAART
    Redefining HIV/AIDS care delivery in the face of human resource scarcity
    Conclusion: closing the gap - one world, one standard

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