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  • 50 Studies Every Neonatologist Should Know

    50 Studies Every Neonatologist Should Know by Zupancic, John; Hay, Susanne; Soll, Roger F.;

    Series: Fifty Studies Every Doctor Should Know;

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    Product details:

    • Publisher OUP USA
    • Date of Publication 20 December 2024

    • ISBN 9780197646953
    • Binding Paperback
    • No. of pages368 pages
    • Size 241x157x22 mm
    • Weight 544 g
    • Language English
    • Illustrations 51 B&W figures
    • 564

    Categories

    Short description:

    50 Studies Every Neonatologist Should Know presents a selection of seminal trials in neonatology, including both cornerstones of practice and frontiers in trial design. The included trials cover a broad range of care topics in neonatology, as well as important learning points in a number of dimensions. The text explores each trial in a dedicated chapter, with a concise summary of methods and results, accompanied by a brief discussion of special considerations, including risks of bias, interpretation, and implications for practice. Additionally, there is a short interview with the trialist (or an editorial commentary) at the end of each chapter, to give a flavor of the ongoing conversation after trial publication. It is a must-read for neonatologists, trainees, or anyone involved in neonatal care or trial design.

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    Long description:

    50 Studies Every Neonatologist Should Know presents a selection of seminal trials in neonatology, including both cornerstones of practice and frontiers in trial design. The included trials cover a broad range of care topics in neonatology, as well as important learning points in a number of dimensions. The text explores each trial in a dedicated chapter, with a concise summary of methods and results, accompanied by a brief discussion of special considerations, including risks of bias, interpretation, and implications for practice. Additionally, there is a short interview with the trialist (or an editorial commentary) at the end of each chapter, to give a flavor of the ongoing conversation after trial publication.

    As with all books in the "50 Studies" series, each study was selected using an objective selection criterion that included citations per year, high levels of evidence, clinical studies and trials, and a 3-stage Delphi review by international experts in the field. It is a must-read for neonatologists, trainees, or anyone involved in neonatal care or trial design.

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    Table of Contents:

    Preface from the Series Editor
    Preface
    Contributors
    Intrapartum Care
    1. A Controlled Trial of Antepartum Glucocorticoid Treatment for Prevention of the Respiratory Distress Syndrome in Premature Infants
    Sarah D. McDonald
    2. Prevention of Early-Onset Neonatal Group B Streptococcal Disease with Selective Intrapartum Chemoprophylaxis
    Megan J. Turner and Clyde J. Wright
    3. Reduction of Maternal-Infant Transmission of Human Immunodeficiency Virus Type 1 with Zidovudine Treatment
    Wes Onland and Anton H. van Kaam
    4. A Randomized, Controlled Trial of Magnesium Sulfate for the Prevention of Cerebral Palsy: The BEAM Trial
    Elizabeth Foglia
    Resuscitation
    5. Resuscitation of Asphyxiated Newborn Infants with Room Air or Oxygen: The Resair 2 Trial
    Elizabeth Baker and Peter G. Davis
    6. Delivery Room Management Of The Apparently Vigorous Meconium-Stained Neonate
    Charles Christoph Roehr
    7. Randomized Trial of Occlusive Wrap for Heat Loss Prevention in Preterm Infants: The HeLP Trial
    Anup Katheria
    8. Association of Umbilical Cord Milking Versus Delayed Umbilical Cord Clamping with Death or Severe Intraventricular Hemorrhage among Preterm Infants: The PREMOD2 Trial
    Seh Hyun Kim and Han-Suk Kim
    9. Effect of Sustained Inflations Versus Intermittent Positive Pressure Ventilation on Bronchopulmonary Dysplasia or Death among Extremely Preterm Infants: The SAIL Trial
    Susanne Hay and John Zupancic
    Cardiovascular
    10. Effects of Indomethacin in Premature Infants with Patent Ductus Arteriosus
    Souvik Mitra
    11. Extracorporeal Circulation in Neonatal Respiratory Failure
    Elizabeth Baker and Peter G. Davis
    12. UK Collaborative Randomised Trial of Neonatal Extracorporeal Membrane Oxygenation
    Brianna Liberio and Clyde J. Wright
    13. Inhaled Nitric Oxide in Full-Term and Nearly Full-Term Infants with Hypoxic Respiratory Failure: The NINOS Trial
    Dirk Bassler
    Respiratory
    14. Prevention of Neonatal Respiratory Distress Syndrome by Tracheal Instillation of Surfactant
    Colm P.F. O'Donnell
    15. Collaborative Quality Improvement to Promote Evidence Based Surfactant for Preterm Infants: A Cluster Randomised Trial
    Ashraf Kharrat and Prakesh S. Shah
    16. Pressure-Regulated Volume Control Ventilation Versus Synchronized Intermittent Mandatory Ventilation for Very Low-Birth-Weight Infants
    Erik A. Jensen
    17. Long-Term Effects of Caffeine Therapy for Apnea of Prematurity: The CAP Trial
    Dirk Bassler
    18. Outcome at Two Years of Age of Infants from The DART Study: A Multicenter, International, Randomised, Controlled Trial of Low-Dose Dexamethasone
    Anton H. van Kaam and Wes Onland
    19. Early CPAP Versus Surfactant in Extremely Preterm Infants: The SUPPORT Trial
    Brett J. Manley
    20. Target Ranges of Oxygen Saturation in Extremely Preterm Infants: The SUPPORT Trial
    James I. Hagadorn
    21. A Trial Comparing Noninvasive Ventilation Strategies in Preterm Infants
    Brett J. Manley
    22. High-Flow Nasal Cannulae in Very Preterm Infants after Extubation: The HIPERSPACE Trial
    Charles Christoph Roehr
    Nutrition
    23. Randomised Trial of Early Diet in Preterm Babies and Later Intelligence Quotient
    Michelle Fernandes and Jon Dorling
    24. Vitamin A Supplementation for Extremely-Low-Birth-Weight Infants
    Susanne Hay and Axel R. Franz
    25. Promotion of Breastfeeding Intervention Trial: The PROBIT Trial
    Nicholas D. Embleton
    26. Dextrose Gel for Neonatal Hypoglycemia: The Sugar Babies Trial
    Adel Mohamed, Jyotsna Shah, and Prakesh S. Shah
    27. Effect of Supplemental Donor Human Milk Compared with Preterm Formula on Neurodevelopment of Very Low-Birth-Weight Infants at 18 Months: The DOMINO Trial
    Nicholas D. Embleton
    Thermal
    28. The Influence of the Thermal Environment upon the Survival of Newly Born Premature Infants
    David Osborn
    29. Kangaroo Mother Versus Traditional Care for Newborn Infants.
    Srinivas Murki
    Infectious Disease / Immunology
    30. Palivizumab, A Humanized Respiratory Syncytial Virus Monoclonal Antibody, Reduces Hospitalization from Respiratory Syncytial Virus Infection in High-Risk Infants: The IMpact-RSV Trial
    Brian C. King
    31. Probiotic Effects on Late-Onset Sepsis in Very Preterm Infants: The ProPrems Trial
    Deena Thomas and M. Jeeva Shankar
    32. Valganciclovir for Symptomatic Congenital Cytomegalovirus Disease
    Li Ma
    Hematology
    33. Hemorrhagic Disease of the Newborn
    Anna E. Curley
    34. Effects of Early Erythropoietin Therapy on the Transfusion Requirements of Preterm Infants Below 1250 Grams Birth Weight
    Anna E. Curley
    35. Higher or Lower Hemoglobin Transfusion Thresholds for Preterm Infants: The TOP Trial
    Axel R. Franz
    36. A Randomized Trial of Erythropoietin for Neuroprotection in Preterm Infants: The PENUT Trial
    Nicholas D. Embleton
    37. Randomized Trial of Platelet-Transfusion Thresholds in Neonates: The PlaNeT Trial
    Ravi Mangal Patel
    Ophthalmology
    38. Multicenter Trial of Cryotherapy for Retinopathy of Prematurity, Preliminary Results: The CRYO-ROP Trial
    James I. Hagadorn
    39. Supplemental Therapeutic Oxygen for Prethreshold Retinopathy of Prematurity, Primary Outcomes: The STOP-ROP Trial
    Souvik Mitra
    40. Efficacy of Intravitreal Bevacizumab for Stage 3+ Retinopathy of Prematurity: The BEAT-ROP Trial
    Brian C. King
    Neurology
    41. Long-Term Effects of Indomethacin Prophylaxis in Extremely-Low-Birth-Weight Infants: The TIPP Trial
    Peter W. Fowlie and William McGuire
    42. Effects of Morphine Analgesia in Ventilated Preterm Neonates, Primary Outcomes: The NEOPAIN Trial
    Souvik Mitra
    43. Whole-Body Hypothermia for Neonates with Hypoxic-Ischemic Encephalopathy
    Anton H. van Kaam and Wes Onland
    44. Effectiveness of Sucrose Analgesia in Newborns Undergoing Painful Medical Procedures
    David Osborn
    45. A Randomized Trial of Prenatal Versus Postnatal Repair of Myelomeningocele: The MOMS Trial
    Sara DeMauro
    46. Neurodevelopmental Outcome at Five Years of Age after General Anaesthesia or Awake-Regional Anaesthesia In Infancy: The GAS Trial
    Sara B. DeMauro
    47. Levetiracetam Versus Phenobarbital for Neonatal Seizures: The NEOLEV2 Trial
    Stefan Johansson
    48. Hypothermia for Moderate or Severe Neonatal Encephalopathy in Low-Income and Middle-Income Countries: The HELIX Trial
    Srinivas Murki
    Health Services
    49. Newborn-Care Training and Perinatal Mortality in Developing Countries: The First Breath Trial
    Danielle E.Y. Ehret
    50. Effectiveness of Family Integrated Care in Neonatal Intensive Care Units on Infant and Parent Outcomes
    Evangelia Myttaraki and Chris Gale

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