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  • The Oxford Handbook of the Economics of the Biopharmaceutical Industry

    The Oxford Handbook of the Economics of the Biopharmaceutical Industry by Danzon, Patricia M.; Nicholson, Sean;

    Series: Oxford Handbooks;

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      • Publisher's listprice GBP 160.00
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    Product details:

    • Publisher OUP USA
    • Date of Publication 31 May 2012

    • ISBN 9780199742998
    • Binding Hardback
    • No. of pages624 pages
    • Size 173x249x27 mm
    • Weight 1295 g
    • Language English
    • Illustrations 41 illustrations
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    Short description:

    This volume comprises 18 chapters by leading academics on the economics of the biopharmaceutical industry. Part one examines economic determinants of biopharmaceutical R&D including financing, regulation, and patents. Part two addresses major issues in pharmaceutical markets including pricing, price regulation, and promotion; insurance coverage and effects of patient cost-sharing; the health value of pharmaceuticals; and the endemic use of mergers, acquisitions, and alliances.

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    Long description:

    The biopharmaceutical industry has been a major driver of technological change in health care, producing unprecedented benefits for patients, cost challenges for payers, and profits for shareholders. As consumers and companies benefit from access to new drugs, policymakers around the globe seek mechanisms to control prices and expenditures commensurate with value. More recently the 1990s productivity boom of new products has turned into a productivity bust, with fewer and more modest innovations, and flat or declining revenues for innovative firms as generics replace their former blockbuster products.

    This timely volume examines the economics of the biopharmaceutical industry, with 18 chapters by leading academic health economists. Part one examines the economics of biopharmaceutical innovation including determinants of the costs and returns to new drug development; how capital markets finance R&D and how costs of financing the biopharmaceutical industry compare to financing costs for other industries; the effects of safety and efficacy regulation by the Food and Drug Administration (FDA) and of price and reimbursement regulation on incentives for innovation; and the role of patents and regulatory exclusivities. Part two examines the market for biopharmaceuticals with chapters on prices and reimbursement in the US, the EU, and other industrialized countries, and in developing countries. It looks at the optimal design of insurance for drugs and the effects of cost sharing on spending and on health outcomes; how to measure the value of pharmaceuticals using pharmacoeconomics, including theory, practical challenges, and policy issues; how to measure pharmaceutical price growth over time and recent evidence; empirical evidence on the value of pharmaceuticals in terms of health outcomes; promotion of pharmaceuticals to physicians and consumers; the economics of vaccines; and a review of the evidence on effects of mergers, acquisitions and alliances.

    Each chapter summarizes the latest insights from theory and recent empirical evidence, and outlines important unanswered questions and areas for future research. Based on solid economics, it is nevertheless written in terms accessible to the general reader. The book is thus recommended reading for academic economists and non-economists, and for those in industry and policy who wish to understand the economics of this fascinating industry.

    I was certainly impressed by the breadth of the book... the various authors do a good job in developing the concepts in a readily understood fashion.

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    Table of Contents:

    1. Introduction and overview
    Patricia M. Danzon and Sean Nicholson
    Part 1: Pharmaceutical Innovation
    2. R&D Costs and Returns to New Drug Development: a Review of the Evidence
    Joseph A. DiMasi and Henry G. Grabowki
    3. Financing Research and Development
    Sean Nicholson
    4. Cost of Capital for Pharmaceutical, Biotechnology, and Medical Device Firms
    Scott E. Harrington
    5. The Regulation of Medical Products
    Anup Malani and Tomas Philipson
    6. Incentives to Innovate
    Darius Lakdawalla and Neeraj Sood
    7. Patents and Regulatory Exclusivity
    Rebecca S. Eisenberg
    Part 2: The Market for Pharmaceuticals
    8. Pricing and Reimbursement in U.S. Pharmaceutical Markets
    Ernst R. Berndt and Joseph P. Newhouse
    9. Regulation of Price and Reimbursement For Pharmaceuticals
    Patricia M. Danzon
    10. Drugs and Vaccines for Developing Countries
    Adrian Towse, Eric Keuffel, Hannah E. Kettler, and David B. Ridley
    11. Insurance and Drug Spending
    Mark V. Pauly
    12. Consumer Demand and Health Effects of Cost Sharing
    Dana P. Goldman and Geoff F. Joyce
    13. Measuring Value: Pharmacoeconomics Theory and Practice
    Adrian Towse, Michael Drummond, and Corinna Sorenson
    14. Price Indexes for Prescription Drugs: A Review of the Issues
    Ana Aizcorbe and Nicole Nestoriak
    15. Empirical Evidence on the Value of Pharmaceuticals
    Craig Garthwaite and Mark Duggan
    16. Promotion to Physicians and Consumers
    Don Kenkel and Alan Mathios
    17. The Economics of Vaccines
    Frank A. Sloan
    18. Mergers, Acquisitions, and Alliances
    Henry Grabowski and Margaret Kyle

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