
Role of Signaling Pathways in Brain Tumorigenesis
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63 540 Ft
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Estimated delivery time: In stock at the publisher, but not at Prospero's office. Delivery time approx. 3-5 weeks.
Not in stock at Prospero.
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Delivery time is estimated on our previous experiences. We give estimations only, because we order from outside Hungary, and the delivery time mainly depends on how quickly the publisher supplies the book. Faster or slower deliveries both happen, but we do our best to supply as quickly as possible.
Product details:
- Edition number 1st ed. 2023
- Publisher Springer
- Date of Publication 21 November 2023
- Number of Volumes 1 pieces, Book
- ISBN 9789811584725
- Binding Hardback
- No. of pages218 pages
- Size 235x155 mm
- Weight 560 g
- Language English
- Illustrations 1 Illustrations, black & white 556
Categories
Short description:
This book provides acomprehensive overview of cell signalling pathways and morphogens in the genesis of brain tumours. It also explains the role of brain tumour stem cells in the brain tumour progression. It also elucidates the novel early biomarkers that can be utilized to diagnose brain tumours. It presents the basic developmental pathways and morphogens, including retinoic acid and TGF-b that promote brain tumorigenesis. The chapters illustrate the role of stem cells and stem cells mediated cell signalling pathways including, Sonic hedgehog, Notch, Wnt in the brain tumour growth. The chapters also emphasize the role of transcription factors, mainlyNanog, Sox, BMI1, HIF1 and Pax6 in the brain tumouriogensis. It highlights the role of NF-kb, Myc and neurotrophins in the brain tumour development. Finally, the book summarizes the potential early therapeutic targets and targeted drug discovery for brain tumours.
MoreLong description:
This book provides acomprehensive overview of cell signalling pathways and morphogens in the genesis of brain tumours. It also explains the role of brain tumour stem cells in the brain tumour progression. It also elucidates the novel early biomarkers that can be utilized to diagnose brain tumours. It presents the basic developmental pathways and morphogens, including retinoic acid and TGF-b that promote brain tumorigenesis. The chapters illustrate the role of stem cells and stem cells mediated cell signalling pathways including, Sonic hedgehog, Notch, Wnt in the brain tumour growth. The chapters also emphasize the role of transcription factors, mainlyNanog, Sox, BMI1, HIF1 and Pax6 in the brain tumouriogensis. It highlights the role of NF-kb, Myc and neurotrophins in the brain tumour development. Finally, the book summarizes the potential early therapeutic targets and targeted drug discovery for brain tumours.
MoreTable of Contents:
Introduction of Cell signalling Pathways and Brain Tumours.- Wnt cell signalling pathway and brain tumours development.- Notch cell signalling pathway and Brain Tumours.- Shh cell signalling pathway and paediatric brain tumour ?Medulloblastoma?.- Role of Shh cell signalling pathway in ?glioma?.- Role of stem cell marker NANOG in brain tumours development.- Stem cell factor Sox2 and Brain Tumours Development.- Role of Neurotrophins in brain tumor development.- Role of NFk? in brain tumour development.- Role of Myc in brain tumours development.- Role of P53 in Medulloblastoma Development.- Role of Gene TP53 in glioblastoma development.- Role of HIF-1 in Brain Tumour Development.- EGFR and its role in glioma development.- Role of EFGR in medulloblastoma development.- Role of OCT4 in glioblastoma development.- Role of OCT4 in paediatric brain tumour ?medulloblastoma? development.- Role of Mitogen activated protein (MAP) Kinase in paediatric brain tumour ?medulloblastoma?
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Role of Signaling Pathways in Brain Tumorigenesis
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