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    Neuropathology of Drug Addictions and Substance Misuse Volume 3: General Processes and Mechanisms, Prescription Medications, Caffeine and Areca, Polydrug Misuse, Emerging Addictions and Non-Drug Addictions

    Neuropathology of Drug Addictions and Substance Misuse Volume 3 by Preedy, Victor R;

    General Processes and Mechanisms, Prescription Medications, Caffeine and Areca, Polydrug Misuse, Emerging Addictions and Non-Drug Addictions

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    Product details:

    • Publisher Academic Press
    • Date of Publication 18 May 2016

    • ISBN 9780128006344
    • Binding Hardback
    • No. of pages1106 pages
    • Size 276x215 mm
    • Weight 3300 g
    • Language English
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    Long description:

    Neuropathology of Drug Addictions and Substance Misuse, Volume 3: General Processes and Mechanisms, Prescription Medications, Caffeine and Areca, Polydrug Misuse, Emerging Addictions and Non-Drug Addictions is the third of three volumes in this informative series and offers a comprehensive examination of the adverse consequences of the most common drugs of abuse. Each volume serves to update the reader's knowledge on the broader field of addiction as well as to deepen understanding of specific addictive substances. Volume 3 addresses prescription medications, caffeine, polydrug misuse, and non-drug addictions. Each section provides data on the general, molecular, cellular, structural, and functional neurological aspects of a given substance, with a focus on the adverse consequences of addictions.

    Research shows that the neuropathological features of one addiction are often applicable to those of others, and understanding these commonalties provides a platform for studying specific addictions in more depth and may ultimately lead researchers toward new modes of understanding, causation, prevention and treatment. However, marshalling data on the complex relationships between addictions is difficult due to the myriad of material and substances.

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    Table of Contents:

    Part I. Principles of Addictions, Overviews, Detailed Processes and Mechanisms

    Section A. General Aspects

    Chapter 1. Drugs and the Human Envirome

    Chapter 2. Psychoactive Plants Used during Religious Rituals

    Chapter 3. Substance Use Disorders and Comorbid Mental Illness: A Focus on Epidemiological Data Regarding Mood and Anxiety Disorders

    Chapter 4. Mephedrone and Mephedrone-Based Cocktails: Market, Analysis, Mechanisms of Action, and Toxicity

    Chapter 5. Substance-Induced Psychosis: Conceptual and Diagnostic Challenges in Clinical Practice

    Chapter 6. Sleep and Drug Addiction

    Section B. Molecular and Cellular Aspects

    Chapter 7. Hypothalamic and Midbrain Cells, Tyrosine Hydroxylase, and Implications for Drug Addiction

    Chapter 8. Oxytocin: Providing New Avenues for Treating and Understanding Problematic Drug Use

    Chapter 9. Role of D2-like Heteroreceptor Complexes in the Effects of Cocaine, Morphine, and Hallucinogens

    Chapter 10. Glutamate Receptors and Drug Addiction

    Chapter 11. Effect of Interacting Nonsteroidal Anti-Inflammatory Agents (NSAIDs) and Opioids on Mood: Pharmacodynamic Considerations in Misuse and Abuse

    Chapter 12. A Mini-Review on Different Commonly Used Abusive Drugs and the Interactions of These Drugs and Chinese Herbs

    Chapter 13. Interaction of Drugs of Addiction with DNA

    Chapter 14. Drugs of Abuse and DNA Methylation in the Brain: Ethanol, Cocaine, Amphetamine-Methamphetamine, Heroin, Antidepressants, and Antipsychotics

    Chapter 15. Orexin/Hypocretin System and Drug Addiction

    Chapter 16. Reverse Translational Implications of Genome-Wide Association Studies for Addiction Genetics

    Chapter 17. Polymorphisms in the Delta Opioid Receptor Gene (OPRD1) and Drug Addiction: Candidate Genes, Transgenic Mouse Models, and Genome-Wide Association Studies

    Chapter 18. Drug Addictions and Genetics of the Dopamine Pathway

    Chapter 19. In Silico Chemogenomics Knowledgebase and Computational System Neuropharmacology Approach for Cannabinoid Drug Research

    Chapter 20. Cocaine- and Amphetamine-Regulated Transcript (CART) Peptide and Drug Addiction

    Section C. Structural and Functional Aspects

    Chapter 21. The Cerebellar Landscape of Drug Addiction

    Chapter 22. Movement Dysfunction as a Neuropathology of Illicit Stimulant Abuse

    Chapter 23. Left Hemispheric "Imbalance” in Drug Addiction

    Chapter 24. Co-occurence of Substance Use and Personality Disorders: Epidemiology, Etiopathogenesis, and Treatment

    Chapter 25. Neonatal Abstinence Syndrome: Pharmacological Aspects

    Chapter 26. Comorbidity between Substance Use Disorder and Severe Mental Illness: Dual Diagnosis

    Part II. Prescription Medications: Depressants

    Section A. General Aspects

    Chapter 27. Lormetazepam Addiction

    Chapter 28. Prescribing and Dispensing of Benzodiazepines: Implications for Dependence and Misuse

    Section B. Molecular and Cellular Aspects

    Chapter 29. Bidirectional Plasticity of Hippocampal Glutamate Receptors Is Central to Expression of Benzodiazepine Withdrawal-Anxiety

    Chapter 30. Effect of Chronic Benzodiazepine Exposure on GABAA Receptors: Regulation of GABA/Benzodiazepine Site Interactions

    Chapter 31. The K+-Cl? Cotransporter KCC2 and Zolpidem

    Section C. Structural and Functional Aspects

    Chapter 32. Benzodiazepine Misuse and Addiction. Risk Factors and Adverse Behavioral Aspects

    Chapter 33. Benzodiazepines, Age-Related Pharmacological Changes, and Risk of Falls in Older Adults

    Chapter 34. The Substantia Nigra Pars Reticulata in Sedative-Hypnotic Withdrawal

    Section D. Methods

    Chapter 35. Assays for Benzodiazepines

    Part III. Opioids and Morphine Derivatives

    Section A. General Aspects

    Chapter 36. Weak Opioid Analgesics Abuse and Addiction: A Comparison of the Pharmacology and Pharmacoepidemiology of Codeine, Dihydrocodeine, and Tramadol

    Chapter 37. Maternal Codeine and Its Effect on the Fetus and Neonate: A Focus on Pharmacogenomics, Neuropathology, and Withdrawal

    Chapter 38. Methadone Usage, Misuse, and Addiction Processes: An Overview

    Chapter 39. Tramadol, Usage, Misuse, and Addiction Processes

    Chapter 40. Tramadol Abuse in the Elderly

    Section B. Molecular and Cellular Aspects

    Chapter 41. Oligodendrocyte Responses, Myelination, and Opioid Addiction Treatments

    Chapter 42. Opioids and TRPV1 Receptors

    Chapter 43. Opioids and Serotonin Syndrome: An Example with Tramadol

    Chapter 44. Opioid Dependence and the Adenylyl Cyclase/cAMP Signaling

    Chapter 45. Central Nervous System Penetration of the Opioid Oxycodone

    Chapter 46. Opioid Modulation of Voltage-Gated Calcium Currents

    Chapter 47. The Neonatal Brain and Opioids

    Chapter 48. Contribution of Spinal Cord mTORC1 to Chronic Opioid Tolerance and Hyperalgesia

    Chapter 49. Interaction of Codeine with DNA

    Chapter 50. Fentanyl and Its Impact on Cell Functions

    Chapter 51. Morphine and Trafficking of a Mu Opioid Receptor Interacting Protein WLS

    Chapter 52. Fas, Bcl-2, and Caspase-3 Protein and Morphine Addiction

    Chapter 53. An Overview on Methadone-Intoxicated Patients

    Chapter 54. Genetic Polymorphisms on OPRM1 Involved in Multiple Responses of a Methadone Maintenance Population: Relationships with Insomnia, Libido, Smoking, and Chemokines

    Section C. Structural and Functional Aspects

    Chapter 55. Modulation of Opioid Analgesic Reward by Inflammatory Agents

    Chapter 56. Suicidal Behavior and Prescription Opioid Medication

    Chapter 57. Codeine and Psychomotor Activity

    Chapter 58. Neurobehavior of Neonates Born to Mothers Receiving Opioid Maintenance Treatment: Methadone and Buprenorphine

    Chapter 59. Prenatal Methadone and Behavioral Sensitization Induced by Methamphetamine

    Chapter 60. Treatments for Opioid Dependence and Methadone: Neurological and Behavioral Aspects

    Chapter 61. Cognitive Functioning in Methadone Use

    Chapter 62. Sleep Disturbances in Methadone Maintenance Treatment (MMT) Patients

    Section D. Methods

    Chapter 63. The Neuropathology of Drug Addictions and Substance Misuse: Assays for Fentanyl

    Chapter 64. Assays for Tramadol and Its Metabolites

    Part IV. Stimulants and Other Compounds

    Section A. General Aspects

    Chapter 65. Methylphenidate Abuse: An Overview

    Section B. Molecular and Cellular Aspects

    Chapter 66. The Impact of Methylphenidate on Circadian Rhythms and Clock Gene Expression

    Section C. Structural and Functional Aspects

    Chapter 67. The Characteristics of Acute and Chronic Methylphenidate, Dose, and Route on Female and Male Animal Behavior

    Chapter 68. Methylphenidate and Cognitive Performance

    Chapter 69. Methylphenidate and Suicide

    Chapter 70. The Effect of Methylphenidate on the Ventral Tegmental Area in Adolescent and Adult Animals

    Chapter 71. Dextromethorphan and Dextrorphan as Heuristic Rapid-Acting, Conventional, and Treatment-Resistant Antidepressants, with Substance Abuse Considerations

    Part V. Caffeine and Areca (Betal Nut)

    Section A. General Aspects

    Chapter 72. Caffeine and Taurine and Energy Drink Abuse

    Chapter 73. General Aspects of Areca Nut Addiction

    Section B. Molecular and Cellular Aspects

    Chapter 74. Caffeine, Adenosine A1 Receptors, and Brain Cortex. Molecular Aspects

    Chapter 75. Caffeine and the Developing Brain: Molecular and Cellular Effects

    Section C. Structural and Functional Aspects

    Chapter 76. Effects of Caffeine and Its Cortical Response Studied by Functional Brain Imaging

    Chapter 77. Neurobehavioral Aspects of Caffeine

    Chapter 78. Oral and Systemic Health Effects of Compulsive Areca Nut Use

    Chapter 79. Areca Alkaloids and Schizophrenia

    Chapter 80. Attentional Biases for Betel Nut Cues

    Section D. Methods

    Chapter 81. Quantitative Measurement of Caffeine by Optical Methods

    Chapter 82. Betel Quid Dependence Scale

    Part VI. Dual and Polydrug Abuse

    Chapter 83. Types of Polydrug Usage

    Chapter 84. Polypharmacy of Potentially Addictive Medications and the Elderly

    Chapter 85. New Insight into Alcohol and Nicotine Addiction: Neurobiological Findings and Therapeutical Perspectives

    Chapter 86. Multimodal Magnetic Resonance Neuroimaging and Cognition in Polysubstance Users

    Chapter 87. Neuropathological Studies in Polydrug Abusers

    Part VII. Emerging Addictions and Drugs of Abuse

    Chapter 88. Novel Drugs of Abuse: Cannabinoids, Stimulants, and Hallucinogens

    Chapter 89. Kratom (Mitragyna speciosa) Use, Addiction Potential, and Legal Status

    Chapter 90. Methylxanthines and Drug Dependence: Interactions and Toxicity

    Chapter 91. The Neuropathology of Movement Disorders in 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP) and Methcathinone (Ephedrone) Addictions

    Chapter 92. 25C-NBOMe as a New Hallucinogen

    Chapter 93. Pregabalin Abuse and Addiction

    Part VIII. Non-Drug Addictions as Comparative Neuropathology

    Chapter 94. Internet Gaming Disorder

    Chapter 95. The Neuropathology of Internet Addiction

    Chapter 96. Workaholism: An Addiction to Work

    Chapter 97. Exercise Addiction

    Chapter 98. Compulsive Buying-Features and Characteristics of Addiction

    Chapter 99. Food Addiction: Applying Substance Use Disorder Criteria and Characteristics to Identify Instances of Addictive-Like Eating

    Chapter 100. Bulimia Nervosa as an Addiction

    Chapter 101. Gambling Disorders: A Focus on Genetic Aspects

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