Liquid Biopsy for Cancer
Current Status and Future Challenges
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Product details:
- Edition number 2024
- Publisher Springer Nature Singapore
- Date of Publication 20 February 2026
- Number of Volumes 1 pieces, Book
- ISBN 9789819944170
- Binding Hardback
- No. of pages131 pages
- Size 254x178 mm
- Language English
- Illustrations X, 131 p. 14 illus., 13 illus. in color. Illustrations, black & white 700
Categories
Long description:
Individual tumour molecular profiling and tracking dynamic evolution by treatment related selective pressure are crucial for clinical oncology. However, current tissue biopsy cannot represent spatial and temporal tumour heterogeneity due to sampling bias.
Liquid biopsy is an alternative way of tissue biopsy since it can represent comprehensive molecular signature from multiple distinct lesions and real time tracking is feasible by repeated longitudinal assay during course of treatment.
This book describes current knowledge regarding pre-analytical issues including standardization of blood preparation, analytical variability, clinical application and regulatory agency approval issue, etc. Regarding targets in circulation, it focuses on circulating tumour cells (CTCs), circulating nucleic acid (ctDNA, cell free RNAs), extracellular vesicles, tumour educated platelets, and others (proteins, metabolites).
The book will be a rich source of information and instruction for oncologists and offers stimulating ideas on prospects for further progress in this field.
The translation was done with the help of artificial intelligence. A subsequent human revision was done primarily in terms of content.
MoreTable of Contents:
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Chapter 1. Liquid Biopsy in the Era of Precision Oncology.- Chapter 2. Biological Analytes in Liquid Biopsy.- Chapter 3. Pre-analytical Considerations for Liquid Biopsy.- Chapter 4. Development and Validation of Liquid Biopsy Platforms.- Chapter 5. Clinical Applications of Liquid Biopsy.- Chapter 6. Interpretation and Pitfalls in Liquid Biopsy.- Chapter 7. Circulating Immune Biomarkers.- Chapter 8. Conclusions and Future Directions.
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