Gamete Immunology by Shibahara, Hiroaki; Hasegawa, Akiko;

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Product details:

Edition number 1st ed. 2022
Publisher Springer
Date of Publication 28 August 2023
Number of Volumes 1 pieces, Book

ISBN 9789811696275
Binding Paperback
No. of pages279 pages
Size 235x155 mm
Weight 542 g
Language English
Illustrations 1 Illustrations, black & white

Short description:

This book describes the biology, diagnosis, treatment and the latest research on anti-sperm antibody (ASA) and anti-zona pellucida antibody (AZPA) produced in some infertile patients. It summarizes ASA in both men and women, and presents new research to serve as a guideline for medical treatment, which currently varies considerably. It also discusses the recently identified target antigens of these antibodies, and the latest immunocontraceptive development projects. The book features chapters on AZPA explaining the biological structure and function of the zona pellucida, and describing the abnormality and the antibody. It also provides insights into their evolution, presenting the differences in taxonomy, mammalian physiological functions and the morphologically and immunologically unique human zona pellucida.

Gamete Immunology is a valuable resource for researchers, and postdocs who are curious about new research on ASA and AZPA. It offers clinicians and embryologists who are interested in gamete immunology diverse perspectives as well as the basis for new ideas to treat the antibodies and develop contraceptive vaccinogens.

Long description:

Chapter 1. Historical Background of Immune Infertility Associated with Anti-Sperm Antibody (ASA) in Women.- Chapter 2. Detection of Anti-Sperm Antibody (ASA) in Women.- Chapter 3. Causes of Immune Infertility in Women with Anti-Sperm Antibody (ASA).- Chapter 4. Production of Anti-Sperm Antibody (ASA) in Women.- Chapter 5. Non-Assisted Reproductive Technology (ART) Treatments for Infertile Women with Anti-Sperm Antibody (ASA).- Chapter 6. Assisted Reproductive Technology (ART) as a Treatment for Infertile Women with Anti-Sperm Antibody (ASA).- Chapter 7. Historical Background of Immune Infertility Associated with Anti-Sperm Antibody (ASA) in Men.- Chapter 8. Detection of Anti-Sperm Antibody (ASA) in Men.- Chapter 9. Causes of Immune Infertility in Men with Anti-Sperm Antibody (ASA).- Chapter 10. Production of Anti-Sperm Antibody (ASA) in Men.- Chapter 11. Classical Treatments for Infertile Men with Anti-Sperm Antibody (ASA).- Chapter 12. Assisted Reproductive technology (ART) as A Treatment for Infertile Men with ASA.- Chapter 13. Development of Immunocontraceptives in Famale.- Chapter 14. Development of Immunocontraceptives in Male.- Chapter 15. Wildlife Overpopulation Control.- Chapter 16. Structure of ZP.- Chapter 17. Function of ZP.- Chapter 18. Human ZP.- Chapter 19. ZP in Assisted Reproductive Technology.- Chapter 20. Infertility and Anti-ZP antibody (AZPA).- Chapter 21. ZP-based Immunocontraceptive vaccine.