Drugs and a Methodological Compendium
From bench to bedside
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Estimated delivery time: In stock at the publisher, but not at Prospero's office. Delivery time approx. 3-5 weeks.
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Delivery time is estimated on our previous experiences. We give estimations only, because we order from outside Hungary, and the delivery time mainly depends on how quickly the publisher supplies the book. Faster or slower deliveries both happen, but we do our best to supply as quickly as possible.
Product details:
- Edition number 2023
- Publisher Springer
- Date of Publication 24 September 2023
- Number of Volumes 1 pieces, Book
- ISBN 9789811979514
- Binding Hardback
- No. of pages425 pages
- Size 235x155 mm
- Weight 828 g
- Language English
- Illustrations 1 Illustrations, black & white 540
Categories
Short description:
This book provides a meticulous view on methodological drug discovery and development insights from bench to bedside. The current book threads almost each step encompassing drug the discovery and development of a molecule. The chapters focus on computational modus operandi, pharmacological optimization approaches, modern high-throughput screening methods and in-vitro procedures, role of structural biologists in drug discovery and development, medicinal chemistry approaches for drug design, formulation and drug delivery, in-vivo evaluations of candidate molecules, clinical trial procedures and others. The book also covers specific case studies, regulatory approval proceedings, and industrial view point alongside the aforementioned conceptual layout. And at the same time, the volume integrates medical, biological, medicinal, pharmacological and computational streams, and it is suggested as an ideal guideline to a wide audience including molecular biologists, biochemist, pharmacologists, medicinal chemist, toxicologists, drug discovery and development researchers, and all other students interested in these disciplines.
More
Long description:
This book provides a meticulous view on methodological drug discovery and development insights from bench to bedside. The current book threads almost each step encompassing drug the discovery and development of a molecule. The chapters focus on computational modus operandi, pharmacological optimization approaches, modern high-throughput screening methods and in-vitro procedures, role of structural biologists in drug discovery and development, medicinal chemistry approaches for drug design, formulation and drug delivery, in-vivo evaluations of candidate molecules, clinical trial procedures and others. The book also covers specific case studies, regulatory approval proceedings, and industrial view point alongside the aforementioned conceptual layout. And at the same time, the volume integrates medical, biological, medicinal, pharmacological and computational streams, and it is suggested as an ideal guideline to a wide audience including molecular biologists, biochemist, pharmacologists, medicinal chemist, toxicologists, drug discovery and development researchers, and all other students interested in these disciplines.
MoreTable of Contents:
Chapter 1.Computational and informatics methodologies in Drug Discovery, with focus on Natural Products.- Chapter 2.Structural biology an essential tool for Drug discovery and Development.- Chapter 3.Bioactivity guided fractionation and identification of bioactive molecules: A basic method in drug discovery.- Chapter 4.In?vitro methodologies for the safety assessment of drugs.- Chapter 5.In-vivo models for evaluation of Drug efficacy: Demand and Challenges.- Chapter 6.Preclinical In vivo Drug Development Studies: Limitations, Model Organisms and Techniques.- Chapter 7.Peptide Based Therapeutics and Drug Delivery Systems.- Chapter 8.Basics of Clinical Drug Development: Clinical Trial and Drug Development.- Chapter 9.Trailblazing contemporary frameworks for drug repurposing: A saga on drugs? expedition to disinter the veiled destiny.- Chapter 10.Small molecules as promising tool for targeted cancer therapies: an overview of 21st century.- Chapter 11.Nanoparticles for Targeted DrugDelivery Systems with Cancer Therapy in Perspective.- Chapter 12.Biomimetic approach for the controlled drug delivery through 3D bioactive scaffolds: A novel strategy for tissue engineering applications.- Chapter 13.Perspectives on anti-tuberculosis drug discovery.- Chapter 14.Cofactor-Receptor interactions based pharmacophore design for development of novel inhibitors: A case study against Tuberculosis.- Chapter 15.Insilico identification of potential antivirals against SARS-CoV2 main protease and RBD of spike protein ? A Drug Repurposing Approach.- Chapter16.Anti-malarial drug discovery and development: from bench to bedside.
Drugs and a Methodological Compendium: From bench to bedside
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