Biocatalysis in Asymmetric Synthesis
Publisher: Academic Press
Date of Publication: 1 May 2024
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Product details:
| ISBN13: | 9780443190575 |
| ISBN10: | 0443190577 |
| Binding: | Paperback |
| No. of pages: | 472 pages |
| Size: | 234x191 mm |
| Language: | English |
| 700 |
Category:
Long description:
Biocatalysis in Asymmetric Synthesis, a new volume in the Foundations and Frontiers of Enzymology series, offers an applied discussion on synthesizing biological catalysts using asymmetric synthesis for varying applications. Here, global experts in the field analyze a wide variety of biocatalysts and their physical states, process conditions for their asymmetric synthesis, solvents required during synthesis, and even downstream procedures for the recovery of final products. The book adopts an interdisciplinary approach, merging fundamental biology and its synthetic applications across industries with a wide range of practical examples, from directed evolution to biotransformation and production of novel enzymes and non-conventional catalysts. Throughout the book, the impact and application of biocatalysis in sustainable processing is considered in-depth. This book will also help non-experts in biocatalysis to apply this knowledge in their own research, providing a thorough overview of the ways asymmetric biocatalytic approaches may be adapted for different disciplines and downstream products.
- Explores biocatalysts as exquisite catalysts for fine chiral compound synthesis in different reaction media
- Features both foundational overviews and applied, practical examples across research and industry
- Includes chapter contributions from international leaders in the field
Table of Contents:
1. Introduction to asymmetric synthesis employing biocatalysts
2. Green metrics in biocatalyzed asymmetric synthesis
3. Assessing the optical purity in enzyme-catalyzed asymmetric synthesis
4. Enzyme Flexibility as a key role for stereoselectivity
5. Control of the enantioselectivity in biocatalyzed procedures: Immobilization, medium engineering and directed evolution
6. Hydrolases in asymmetric synthesis
7. Biocatalysis for the selective reduction of carbonyl moeties
8. Synthesis of valuable chiral amines employing transaminases, imine reductases and amine dehydrogenases
9. Biocatalyzed carbon-carbon bond formation in the asymmetric synthesis
10. Synthesis of chiral compounds through biooxidations
11. Asymmetric biocatalysis in non-conventional media: Neat conditions, Eutectic Solvents and supercritical conditions
12. Multicatalytic asymmetric processes employing enzymes and chemocatalysts13. Asymmetric biotransformations employing whole cell systems
14. Thermophilic enzymes in asymmetric catalysis
15. Novel biocatalytic applications employing "novel to nature" enzymes
16. Development of asymmetric biotransformations: Flow biocatalysis, photobiocatalysis and microwave biocatalysis
17. Patents based on biocatalytic methods for the synthesis of valuable chiral compounds
18. Industrial asymmetric Biocatalysis
2. Green metrics in biocatalyzed asymmetric synthesis
3. Assessing the optical purity in enzyme-catalyzed asymmetric synthesis
4. Enzyme Flexibility as a key role for stereoselectivity
5. Control of the enantioselectivity in biocatalyzed procedures: Immobilization, medium engineering and directed evolution
6. Hydrolases in asymmetric synthesis
7. Biocatalysis for the selective reduction of carbonyl moeties
8. Synthesis of valuable chiral amines employing transaminases, imine reductases and amine dehydrogenases
9. Biocatalyzed carbon-carbon bond formation in the asymmetric synthesis
10. Synthesis of chiral compounds through biooxidations
11. Asymmetric biocatalysis in non-conventional media: Neat conditions, Eutectic Solvents and supercritical conditions
12. Multicatalytic asymmetric processes employing enzymes and chemocatalysts13. Asymmetric biotransformations employing whole cell systems
14. Thermophilic enzymes in asymmetric catalysis
15. Novel biocatalytic applications employing "novel to nature" enzymes
16. Development of asymmetric biotransformations: Flow biocatalysis, photobiocatalysis and microwave biocatalysis
17. Patents based on biocatalytic methods for the synthesis of valuable chiral compounds
18. Industrial asymmetric Biocatalysis
