Short description:

Autoimmune Diseases in Endocrinology is a comprehensive and novel text that examines key features that predispose individuals to autoimmune diseases. The text begins with three introductory chapters which provide sufficient information so that anyone, including those without a background in recent immunology, will be able to understand the developments in the field. The next and largest section of the book concerns autoimmune thyroid disease, and authors of these chapters take the reader through the basic epidemiology, genetic and environmental risk factors, immunopathogenesis, and the diagnostic and management aspect of the disease. The next section discusses Type 1 diabetes mellitus. In the final section, authors explain other autoimmune endocrinopathies, including Addison?s disease, premature ovarian failure, autoimmune hypophysitis, and autoimmune polyglandular syndrome types 1 and 2. Comprehensive and timely, Autoimmune Diseases in Endocrinology will become an essential reference for all endocrinologists and internal medicine practitioners working in this field.

Long description:

Autoimmune Diseases in Endocrinology is a comprehensive and novel text that examines key features that predispose individuals to autoimmune diseases. The text begins with three introductory chapters which provide sufficient information so that anyone, including those without a background in recent immunology, will be able to understand the developments in the field. The next and largest section of the book concerns autoimmune thyroid disease, and authors of these chapters take the reader through the basic epidemiology, genetic and environmental risk factors, immunopathogenesis, and the diagnostic and management aspect of the disease. The next section discusses Type 1 diabetes mellitus. In the final section, authors explain other autoimmune endocrinopathies, including Addison?s disease, premature ovarian failure, autoimmune hypophysitis, and autoimmune polyglandular syndrome types 1 and 2. Comprehensive and timely, Autoimmune Diseases in Endocrinology will become an essential reference for all endocrinologists and internal medicine practitioners working in this field.

From the reviews:

"Many endocrine diseases have an autoimmune etiology. This book focuses on these disorders and provides an understanding of how dysregulation of the immune system contributes to disease pathogenesis. ? This will be most suitable for individuals studying autoimmune endocrine disorders. It also will be helpful to endocrinologists who want to learn more about this important subject. ? This is a great resource for physicians or researchers who wish to learn more about autoimmune endocrine disorders, particularly ? autoimmune thyroid disease and Type 1 diabetes." (Ronald N Cohen, Doody?s Review Service, March, 2008)

"This text is written in a way that allows either a superficial or in-depth approach toward understanding how dysfunction of the immune system produces many different endocrine diseases. ? Each chapter begins with a concise summary, telling the reader what will be covered. This is helpful, like a preacher telling you what the sermon will be covering. ? will remain a helpful addition to my library as patients are seen, diagnoses sought, and treatment rendered." (Samuel P. Marynick, Baylor University Medical Center Proceedings, Vol. 21 (4), September, 2008)

Table of Contents:

Introductory Chapters.- Basic Mechanisms in Autoimmunity.- Immunogenetic Factors in Autoimmunity.- Environmental Factors in Autoimmune Endocrinopathies.- Autoimmune Thyroid Disease.- Animal Models of Autoimmune Thyroid Disease.- Thyroid Autoantigens.- Graves? Disease.- Autoimmune Hypothyroidism.- Postpartum Thyroiditis.- Thyroid-Associated Ophthalmopathy and Dermopathy.- Type 1 Diabetes Mellitus.- Animal Models of Type 1 Diabetes Mellitus.- Islet Cell Autoantigens.- Other Autoimmune Endocrinopathies.- Type 1 Diabetes Mellitus.- Addison?s Disease.- Premature Ovarian Failure.- Autoimmune Hypophysitis.- Autoimmune Polyglandular Syndrome Type 1.- Autoimmune Polyglandular Syndrome Type 2.