Signaling by Toll-Like Receptors
Kiadás sorszáma: 1
Kiadó: CRC Press
Megjelenés dátuma: 2019. október 7.
Normál ár:
Kiadói listaár:
GBP 59.99
GBP 59.99
Az Ön ára:
26 077 (24 836 Ft + 5% áfa )
Kedvezmény(ek): 10% (kb. 2 898 Ft)
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A termék adatai:
| ISBN13: | 9780367387181 |
| ISBN10: | 0367387182 |
| Kötéstípus: | Puhakötés |
| Terjedelem: | 224 oldal |
| Méret: | 234x156 mm |
| Súly: | 408 g |
| Nyelv: | angol |
| 152 |
Témakör:
Rövid leírás:
The recent discovery of an ancient family of toll-like receptors (TLRs) in the immune system has substantially enhanced the potential for a variety of therapies, for both failing immune systems, which leaves the body open to infection or over-active ones, which can lead to chronic inflammation. Signaling by Toll-Like Receptors provides a comprehensive review of important techniques in molecular biology, cell biology, biochemistry, genetics, and immunology and their critical application to the study of toll-like receptor structure, biological function, and the intracellular signaling triggered by these receptors, as well as the high promise for uncovering effective pharmaceutical targets.
Hosszú leírás:
The discovery of toll-like receptors (TLRs) spurred the field of innate immunity into a renaissance after many years of neglect. Since then, TLR research has grown at an exponential rate. Taking an integrated methodological approach, Signaling by Toll-Like Receptors offers a comprehensive review of important techniques in molecular biology, cell biology, biochemistry, genetics, and immunology and their critical application to the study of toll-like receptor structure, biological function, and the intracellular signaling triggered by these receptors.
Tartalomjegyzék:
Assessing the Response of Cells to TLR Stimulation. TLR Ligands in Experimental Settings: Their Purity and Specificity. Analysis of TLR Expression, Regulation, and Signaling. Intracellular Trafficking of Toll-Like Receptors. The Role of Small RhoGTPases in TLR Signaling. Use of Engineered &&&946;-Lactamase Fragment Complementation to Detect the Associations of Toll-Like Receptors and Signaling Adaptors. Use of Toll-Like Receptor Chimeras to Dissect Mechanisms of Receptor Localization and Signaling. Engagement of Toll-Like Receptors Modulates Chemokine Receptor Signaling. Role of Toll-Like Receptor Signaling in Central Nervous System Infections. The Influence of Injury on Toll-Like Receptor Responses. Index.
