B Cells in Immunity and Tolerance

B Cells in Immunity and Tolerance

 
Kiadás sorszáma: 1st ed. 2020
Kiadó: Springer
Megjelenés dátuma:
Kötetek száma: 1 pieces, Book
 
Normál ár:

Kiadói listaár:
EUR 160.49
Becsült forint ár:
66 226 Ft (63 072 Ft + 5% áfa)
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60 928 (58 026 Ft + 5% áfa )
Kedvezmény(ek): 8% (kb. 5 298 Ft)
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  példányt

 
 
 
 
A termék adatai:

ISBN13:9789811535314
ISBN10:98115353111
Kötéstípus:Keménykötés
Terjedelem:181 oldal
Méret:254x178 mm
Súly:610 g
Nyelv:angol
Illusztrációk: 5 Illustrations, black & white; 30 Illustrations, color
215
Témakör:
Rövid leírás:

This book contains twelve chapters contributed by prestigious international experts who are at the forefront of B cell research, and aims to provide a cutting-edge and comprehensive overview of all aspects of B cells, including B cell development, maturation and activation, germinal center reaction, memory and plasma cell differentiation, and antibody-mediated positive and negative regulation of humoral immune responses. There are also three chapters describing human diseases caused by B cell abnormalities, including primary antibody deficiencies, autoimmune diseases, and B cell malignancies. We hope that this book will become a standard and routine reference for both basic researchers and clinicians.


Hosszú leírás:

This book contains twelve chapters contributed by prestigious international experts who are at the forefront of B cell research, and aims to provide a cutting-edge and comprehensive overview of all aspects of B cells, including B cell development, maturation and activation, germinal center reaction, memory and plasma cell differentiation, and antibody-mediated positive and negative regulation of humoral immune responses. There are also three chapters describing human diseases caused by B cell abnormalities, including primary antibody deficiencies, autoimmune diseases, and B cell malignancies. We hope that this book will become a standard and routine reference for both basic researchers and clinicians.




Tartalomjegyzék:
B cell development and maturation.- B cell receptor signalling.- Involvement of reactive oxygen species (ROS) in BCR signaling as a second messenger.- Germinal center reaction.- Memory B cells in local and systemic sites.- Regulation of plasma cell differentiation.- Regulation of humoral immune responses and B cell tolerance by the IgM Fc receptor.- Regulatory B cells.- Diversified IgA-bacteria interaction in gut homeostasis.- Primary antibody deficiencies.- B cell-mediated autoimmune diseases.- B cell lymphomas.