Antibiotics and Antibiotic Resistance in the Environment

Antibiotics and Antibiotic Resistance in the Environment

 
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Kiadó: CRC Press
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A termék adatai:

ISBN13:9780367575175
ISBN10:0367575175
Kötéstípus:Puhakötés
Terjedelem:136 oldal
Méret:246x174 mm
Súly:249 g
Nyelv:angol
233
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Rövid leírás:

 This book will review the available evidence and hypotheses on where antibiotic resistance is coming from and for how long has been there. It will discuss involved maintenance pressures, resistance spread, traits and laboratory and in-silico strategies to further investigate antibiotic resistance.

Hosszú leírás:

The presence of antibiotics, antibiotic resistance genes, and antibiotic resistant bacteria in the environment (i.e., outside of clinical settings, such as antibiotic-treated patients or antibiotic-impregnated locations, such as hospitals) is a cause of growing worldwide concern, as it reveals the extensive impact of antibiotic abuse and other human-related pressures upon microbes. Also, the potential clinical and environmental impact of the presence of antibiotic resistance outside the obvious clinical settings is mostly unknown, but could be unexpectedly large, as resistance in clinical conditions can be seen as a very small "tip of the iceberg". The field of detecting and measuring resistance in the environment has rapidly evolved from mostly anecdotal reports at the end of the 1990s, to a systematic search of organisms and genes in a wide variety of settings, from ancient permafrost to migratory birds. This book will review the available evidence and hypotheses on where this resistance is coming from and for how long it has been there; what are the selective and maintenance pressures involved, and how is resistance spreading; what are the known and possible traits that are being selected and spread along with antibiotic resistance ones; what are the laboratory and in-silico strategies to look into this issue, and their advantages and disadvantages.



For readers with a basic background in biology, this book provides a very useful discussion of most aspects of this topic, including definitions of antibiotics and resistance, the mechanisms responsible for resistance, and the practices that contribute to this problem.

H. E. Pence, SUNY College at Oneonta, written in Choice Magazine (September 2016 issue)

Tartalomjegyzék:
1 Definitions and Basic Concepts; 2 Have Antibiotics and Antibiotic Resistance Genes Always Been Out There?; 3 Human-Related Release of Antibiotics into the Environment; 4 Spread of Resistant Organisms from Human Settlements into the Environment; 5 Impact of Antibiotics and Resistance in Non-Clinical Settings