Translational Research and Onco-Omics Applications in the Era of Cancer Personal Genomics

Translational Research and Onco-Omics Applications in the Era of Cancer Personal Genomics

 
Edition number: 1st ed. 2019
Publisher: Springer
Date of Publication:
Number of Volumes: 1 pieces, Book
 
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Product details:

ISBN13:9783030240998
ISBN10:3030240991
Binding:Hardback
No. of pages:171 pages
Size:254x178 mm
Weight:719 g
Language:English
Illustrations: 19 Illustrations, color
172
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Short description:

This book presents concise chapters written by internationally respected experts on various important aspects of translational cancer genomics, offering a comprehensive overview of the onco-omics applications in the new era of cancer personal genomics research field. Being a complex disease that affects millions of people worldwide, cancer research has assumed great significance. Translational cancer research transforms scientific discoveries in the laboratory into clinical application to reduce incidence of cancer, morbidity and mortality. In the other hand, personalized medicine in cancer is the concept that selection of a treatment should be tailored according to the individual patient?s specific genomic characteristics, including mutations, chromosomal aberrations, protein interactions, and even more, considering the immune system, the metabolism and in the near future the microbiome, all areas nowadays related in the prognosis and treatment of cancer patients. These contributionsare either critical reviews or clinical and basic research reports. The topics discussed here include evidence-based medicine and provides useful information on translational cancer research to clinicians and biomedical scientists in order to offer another vision of cancer origin beyond the traditional causes or the oncogenic maintenance concept proposed by the oncogene addiction theory.

Long description:

Being a complex disease that affects millions of people world over, cancer research has assumed great significance. Translational cancer research transforms scientific discoveries in the laboratory into clinical application to reduce incidence of cancer, morbidity and mortality. On the other hand, personalized medicine in cancer is the concept that selection of a treatment should be tailored according to the individual patient?s specific genomic characteristics, including mutations, chromosomal aberrations, protein interactions, and SNPs, and even more, taking into account the inmume system, the metabolism and maybe in the next future also the microbiome. 

Table of Contents:

Preface.- Pharmaco-Geno-Proteo-Metabolomics and Translational Research in Cancer.- Next generation sequencing (NGS): a revolutionary technology in pharmacogenomics and personalized medicine in Cancer.- Pharmaco-epigenomics: on the road of translation medicine.- Design and Implementing Pharmacogenomics Study in Cancer.- Onco-omics approaches and applications in Clinical Trials for Cancer patients.- Issues and Ethical Considerations in Pharmaco-oncogenomics.- Pharma-oncogenomics in the era of personal genomics: a quick guide to online resources and tools.- Inmuno-Oncology in the era of Personalized Medicine.- CAR T Cell and Personalized Medicine.- Oncobiome at the forefront of a novel molecular mechanism to understand the Microbiome and Cancer.- Nutrition, Cancer and Personalized Medicine.- Index.