LC-MS in Drug Analysis
EUR 117.69
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ISBN13: | 9781493993970 |
ISBN10: | 1493993976 |
Binding: | Paperback |
No. of pages: | 274 pages |
Size: | 254x178 mm |
Weight: | 740 g |
Language: | English |
Illustrations: | 12 Illustrations, black & white; 24 Illustrations, color |
169 |
This second edition provides detailed LC-MS(/MS) procedures for the analysis of compounds of clinical and toxicological significance. Chapters detail new and updated methods for analyzing drugs focusing on advances in technology, alternate matrices, and rapidly-changing classes of drugs of abuse, compounds pertinent to toxicology, and therapeutic agents. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and cutting-edge, LC-MS in Drug Analysis: Methods and Protocols, Second Edition aims to ensure successful results in the further study of this vital field.
This second edition provides detailed LC-MS(/MS) procedures for the analysis of compounds of clinical and toxicological significance. Chapters detail new and updated methods for analyzing drugs focusing on advances in technology, alternate matrices, and rapidly-changing classes of drugs of abuse, compounds pertinent to toxicology, and therapeutic agents. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and cutting-edge, LC-MS in Drug Analysis: Methods and Protocols, Second Edition aims to ensure successful reults in the further study of this vital field.
1. An Introduction to Drug Testing ? The Expanding Role of Mass Spectrometry
Christine L.H. Snozek, Loralie J. Langman, and Steven W. Cotten
2. Quantification of Eight Cannabinoids Including Cannabidiol in Human Urine Via Liquid Chromatography Tandem Mass Spectrometry
Karl B. Scheidweiler and Allan J. Barnes
3. Analysis of Benzodiazepines for Drug Facilitated Assaults and Abuse Settings (Urine)
Olaf H. Drummer, Matthew Di Rago, and Dimitri Gerostamoulos
4. Targeted Opioid Screening Assay for Pain Management Using High Resolution Mass Spectrometry
Darlington Danso, Loralie J. Langman, and Paul J. Jannetto
5. Measurement of Buprenorphine and Norbuprenorphine in Urine
Andrea R. Terrell, Vipin Adhlakha, and Poluru Reddy
6. Quantitation of Tapentadol by Liquid Chromatography ? Tandem Mass Spectrometry
Graham R. Jones and Russell P. Handy
7. Therapeutic Drug Monitoring of Lacosamide by LC-MS/MS
He Sarina Yang and Leslie Edinboro
8. LC-MS/MS method for the quantification of the Leflunomide metabolite, Teriflunomide, in Human Serum/Plasma
Geoffrey S. Rule, Alan L. Rockwood, and Kamisha L. Johnson-Davis
9. Analysis of Tryptic Peptides from Therapeutic Monoclonal Antibodies using LC-MS/MS
Maria Alice Vieira Willrich
10. Quantification of Methotrexate in Human Serum and Plasma by Liquid Chromatography Tandem Mass Spectrometry
Gabrielle N. Winston-McPherson, Michael Schmeling, and Andrew N. Hoofnagle
11. Simultaneous Determination of Tacrolimus and Cyclosporine A in Whole Blood by Ultra-Fast LC-MS/MS
Matthew W Bjergum, Paul J Jannetto, and Loralie J Langman,
12. Liquid Chromatography-tandem Mass Spectrometry (LC-MS/MS) Method to Quantify Gabapentin and Pregabalin in Urine
Stephen Merrigan and Kamisha L. Johnson-Davis1
13. The Evolving Landscape of Designer Drugs
Sherri L. Kacinko and Donna M. Papsun
14. Analysis of Synthetic Cannabinoid Metabolites by Liquid Chromatography-Tandem Mass Spectrometry
Gregory C. Janis
15. Quantification of Designer Opioids by Liquid Chromatography Tandem Mass Spectrometry
Sherri L. Kacinko and Joseph W. Homan
16. Screening Analysis for Designer Stimulants by LC-MS/MS
Piotr Adamowicz and Bogdan Tokarczyk
17. Drug Screening Using Liquid Chromatography Quadrupole Time of Flight (LC-QqTOF) Mass Spectrometry
Jennifer M. Colby and Kara L. Lynch
18. Alternate Matrices ? Meconium, Cord Tissue, Hair, and Oral Fluid
Kendra L. Palmer and Matthew D. Krasowski
19. Salt-assisted Liquid-Liquid Extraction of Meconium for Analysis of Cocaine and Amphetamines by Liquid Chromatography-tandem Mass Spectrometry
Melissa M. Goggin and Gregory C. Janis
20. Detection of In Utero Cannabis Exposure in Umbilical Cord Tissue by A Sensitive Liquid Chromatography?Tandem Mass Spectrometry Method
Fang Wu, Triniti L. Scroggin, and Gwendolyn A. McMillin
21. Quantitation of Ethyl ?-D-glucuronide in Human Umbilical Cord Tissue by Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Simuli L. Wabuyele and Gwendolyn A. McMillin
22. Analysis of Drugs in Oral Fluid using LC-MS/MS
Cynthia Coulter and Christine Moore
23. Determination of Cocaine and Metabolites in Dried Blood Spots by LC-MS/MS
Lars Ambach and Christophe Stove