Brain Tumors

Brain Tumors

 
Edition number: 1st ed. 2021
Publisher: Springer
Date of Publication:
Number of Volumes: 1 pieces, Book
 
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Product details:

ISBN13:9781071608555
ISBN10:107160855X
Binding:Hardback
No. of pages:370 pages
Size:254x178 mm
Weight:925 g
Language:English
Illustrations: 11 Illustrations, black & white; 64 Illustrations, color; 64 Tables, color
255
Category:
Short description:

This volume explores the latest models and techniques used to study brain tumor biology. Chapters in this book are organized into four sections: in vivo models, ex vivo models, treatments in mice, and clinical imaging. Some of the topics covered in this book are in vivo preclinical models of lower-grade gliomas, medulloblastoma, and brain metastases; ex vivo methods for glioblastoma patient-derived cell lines and organotypic brain cultures for metastasis; in vivo treatments of preclinical models that assess neurological function, dynamic immunotherapy, and neurological impacts of brain irradiation; and clinical imaging and modeling, such as biomechanics and vascular perfusion. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. 

Cutting-edge and practical, Brain Tumors is a valuable resource that will help readers understand the heterogeneity of the techniques used to study the complexity of brain tumors. 

Long description:
This volume explores the latest models and techniques used to study brain tumor biology. Chapters in this book are organized into four sections: in vivo models, ex vivo models, treatments in mice, and clinical imaging. Some of the topics covered in this book are in vivo preclinical models of lower-grade gliomas, medulloblastoma, and brain metastases; ex vivo methods for glioblastoma patient-derived cell lines and organotypic brain cultures for metastasis; in vivo treatments of preclinical models that assess neurological function, dynamic immunotherapy, and neurological impacts of brain irradiation; and clinical imaging and modeling, such as biomechanics and vascular perfusion. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. 

Cutting-edge and practical, Brain Tumors is a valuable resource that will help readers understand the heterogeneity of the techniques used to study the complexity of brain tumors. 

Table of Contents:
Series Preface?
Acknowledgements?
Preface?
Table of Contents?
Contributing Authors?

Part I In Vivo Models

1.Mouse Models of Diffuse Lower-Grade Gliomas of the Adult
Sofia Archontidi, Sandra Joppé, Yanis Khenniche, Chiara Bardella, and Emmanuelle Huillard

2.In Vivo Medulloblastoma Modeling
Liliana Mirabal-Ortega, Magalie Larcher, Morgane Morabito, Chloé Foray, Bertrand Duvillié, Alain Eych?ne, and Celio Pouponnot

3.In Vivo Models of Brain Metastases
Christina S. Wong 

4.Intravital Imaging of Brain Tumors
Cathy Pichol-Thievend, Boris Julien, Océane Anézo, Beatrice Philip, and Giorgio Seano

Part II Ex Vivo Models

5.Glioblastoma Patient-Derived Cell Lines: Generation of Non-Adherent Cellular Models from Brain Tumors
Joris Guyon, Tiffanie Chouleur, Andreas Bikfalvi, and Thomas Daubon

6.Organotypic Brain Cultures for Metastasis Research
Lucía Zhu and Manuel Valiente

7.Human Glioblastoma Organoids to Model Brain Tumor Heterogeneity Ex Vivo
W. Dean Pontius, Lisa C. Wallace, Katrina Fife, and Christopher G. Hubert

8.In Vitro Mechanobiology of Glioma: Mimicking the Brain Blood Vessels and White Matter Tracks Invasion Paths
Pascale Monzo, Michele Crestani, and Nils C. Gauthier

Part III Treatments in Mice

9.Assessing Neurological Function in Brain Tumor Mouse Model
Xing Gao, Limeng Wu, Raquel D. Thalheimer, Jie Chen, Yao Sun, Grace Y. Lee, Scott R. Plotkin, and Lei Xu

10.Dynamic Immunotherapy Study in Brain Tumor-Bearing Mice
Luiz Henrique Medeiros Geraldo, Yunling Xu, and Thomas Mathivet 

11.Experimental and Preclinical Tools to Explore the Main Neurological Impacts of Brain Irradiation: Current Insights and Perspectives
Laura Mouton, Monica Ribeiro, Fawzi Boumezbeur, Denis Le Bihan, Marc-André Mouthon, Damien Ricard, François Boussin, and Pierre Verrelle

Part IV Clinical Imaging

12.Mechano-Biological Features in the Patient-Specific Computational Model of Glioblastoma
Francesco Acerbi, Abramo Agosti, Jacopo Falco, Stefano Marchesi, Ignazio G. Vetrano, Francesco DiMeco, Alberto Bizzi, Paolo Ferroli, Giorgio Scita, and Pasquale Ciarletta 

13.Magnetic Resonance Imaging for Quantification of Brain Vascular Perfusion
Line Brennhaug Nilsen and Kyrre Eeg Emblem

14.MRI Morphometry in Brain Tumors: Challenges and Opportunities in Expert, Radiomic, and Deep-Learning Based Analyses
Marco C. Pinho, Pallavi Tiwari, Kaustav Bera, and Niha Beig

Subject Index List...